CAS No.: 409345-29-5
JNJ16259685 Catalog No. CSN18977
JNJ16259685 is a selective antagonist at the mGlu1 receptors, and inhibits the synaptic activation of mGlu1 in a concentration-dependent manner with IC50 of 19 nM.
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Hodgson RA, Hyde LA, et al. Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination. Pharmacol Biochem Behav. 2011 Apr;98(2):181-7.
- [2] Navarro JF, De Castro V, et al. JNJ16259685, a selective mGlu1 antagonist, suppresses isolation-induced aggression in male mice. Eur J Pharmacol. 2008 May 31;586(1-3):217-20.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 409345-29-5 | 储存条件 |
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| 分子式 | C20H23NO3 | 运输 | 蓝冰 | |
| 分子量 | 325.40 | 别名 |
