CAS No.: 374559-48-5
Istaroxime HCl Catalog No. CSN18248
Synonyms: PST2744 hydrochloride;PST-2744 HCl;Istaroxime HCl
Istaroxime HCl is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Istaroxime HCl is a potent inhibitor of Na+,K+-ATPase with IC50 of 0.11 μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Gobbini M, Armaroli S, et al. Novel analogues of Istaroxime, a potent inhibitor of Na(+),K(+)-ATPase: Synthesis, structure-activity relationship and 3D-quantitative structure-activity relationship of derivatives at position 6 on the androstane scaffold. Bioorg Med Chem. 2010 Jun 15;18(12):4275-99.
- [2] Gobbini M, Armaroli S, et al. Novel analogues of istaroxime, a potent inhibitor of Na+,K+-ATPase: synthesis and structure-activity relationship. J Med Chem. 2008 Aug 14;51(15):4601-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 374559-48-5 | 储存条件 |
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| 分子式 | C21H33ClN2O3 | 运输 | 蓝冰 | |
| 分子量 | 396.95 | 别名 | PST2744 hydrochloride;PST-2744 HCl;Istaroxime HCl;PST-2744 |
