CAS No.: 1262238-11-8
INCB3344 Catalog No. CSN17640
INCB3344 is a potent and selective small molecule antagonist of the mouse CCR2 receptor and inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 = 10 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Xue CB, Wang A, et al. Discovery of INCB3344, a potent, selective and orally bioavailable antagonist of human and murine CCR2. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7473-8.
- [2] Brodmerkel CM, Huber R, et al. Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344. J Immunol. 2005 Oct 15;175(8):5370-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1262238-11-8 | 储存条件 |
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| 分子式 | C29H34F3N3O6 | 运输 | 蓝冰 | |
| 分子量 | 577.59 | 别名 |
