CAS No.: 1354799-87-3
Ilginatinib maleate Catalog No. CSN18967
Synonyms: NS-018 maleate;NS-018
NS-018 maleate is an ATP-competitive small-molecule inhibitor of JAK2 with IC50 of 470?nM in Ba/F3-JAK2V617F cells .
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Kuroda J, Kodama A, et al. NS-018, a selective JAK2 inhibitor, preferentially inhibits CFU-GM colony formation by bone marrow mononuclear cells from high-risk myelodysplastic syndrome patients. Leuk Res. 2014 May;38(5):619-24.
- [2] Nakaya Y, Shide K, et al. Efficacy of NS-018, a potent and selective JAK2/Src inhibitor, in primary cells and mouse models of myeloproliferative neoplasms. Blood Cancer J. 2011 Jul;1(7):e29.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1354799-87-3 | 储存条件 |
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| 分子式 | C25H24FN7O4 | 运输 | 蓝冰 | |
| 分子量 | 505.50 | 别名 | NS-018 maleate;NS-018 |
