CAS No.: 1239358-86-1
Ilginatinib Catalog No. CSN17611
Synonyms: NS-018
NS-018 is a highly selective JAK2 inhibitor.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01423851 Primary Myelofibrosis ... more >> Post-Polycythemia Vera Myelofibrosis Post-Essential Thrombocythemia Myelofibrosis Collapse << Phase 1 Phase 2 Active, not recruiting October 2019 United States, Arizona ... more >> Mayo Clinic Scottsdale Recruiting Scottsdale, Arizona, United States, 85259-5499 United States, California UC San Diego Moores Cancer Center San Diego, California, United States, 92093-0698 United States, Florida Mayo Clinic, Jacksonville Jacksonville, Florida, United States, 32224 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 University of Chicago Chicago, Illinois, United States, 60637 United States, Massachusetts Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, New York Weill Cornell Medical College New York, New York, United States, 10021 United States, Texas MD Anderson Cancer Center, Department of Leukemia Houston, Texas, United States, 77030 Collapse << - 参考文献
- [1] Nakaya Y, Shide K, et al. Effect of NS-018, a selective JAK2V617F inhibitor, in a murine model of myelofibrosis. Blood Cancer J. 2014 Jan 10;4:e174.
- [2] Kuroda J, Kodama A, et al. NS-018, a selective JAK2 inhibitor, preferentially inhibits CFU-GM colony formation by bone marrow mononuclear cells from high-risk myelodysplastic syndrome patients. Leuk Res. 2014 May;38(5):619-24.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1239358-86-1 | 储存条件 |
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| 分子式 | C21H20FN7 | 运输 | 蓝冰 | |
| 分子量 | 389.43 | 别名 | NS-018 |
