CAS No.: 467459-31-0
Idalopirdine Catalog No. CSN18286
Synonyms: Lu AE58054
Lu AE58054 is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02371707 Healthy Phase 1 Completed - United Kingdom ... more >> Covance Leeds, United Kingdom Collapse << NCT02006641 Alzheimer's Disease Phase 3 Completed - - NCT02006654 Alzheimer's Disease Phase 3 Completed - - - 更多
- 参考文献
- [1] Witten L, Bang-Andersen B, et al. Characterization of [³H] Lu AE60157 ([³H] 8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine₆ (5-HT₆) receptors in vivo. Eur J Pharmacol. 2012 Feb 15;676(1-3):6-11.
- [2] Arnt J, Bang-Andersen B, et al. Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. Int J Neuropsychopharmacol. 2010 Sep;13(8):1021-33.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 467459-31-0 | 储存条件 |
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| 分子式 | C20H19F5N2O | 运输 | 蓝冰 | |
| 分子量 | 398.37 | 别名 | Lu AE58054 |
