CAS No.: 2235382-05-3
HDAC6 degrader 9c Catalog No. CSN22299
Synonyms: dHDAC6 9c
HDAC6 degrader 9c (dHDAC6 9c) is a bifunctional molecule (dHDAC6) that could selectively degrade HDAC6, by conjugating non-selective HDAC inhibitor to a thalidomide-type E3 ligase ligand; causes degradation of HDAC6 in a dose dependent manner (DC50=34 nM), upregulate the level of acetylated α-tubulin at 1.1 uM; shows the maximal effect of HDAC6 degradation at 80 nM in the MM.1S cell line.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2235382-05-3 | 储存条件 |
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| 分子式 | C37H45N9O10 | 运输 | 蓝冰 | |
| 分子量 | 775.81 | 别名 | dHDAC6 9c |
