CAS No.: 871543-07-6
H-1152 2HCl/H-1152二盐酸盐 Catalog No. CSN16045
Synonyms: H-1152 2HCl
H-1152 2HCl, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Kroll J, Epting D, et al. Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H893-9.
- [2] Ikenoya M, Hidaka H, et al. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002 Apr;81(1):9-16.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 871543-07-6 | 储存条件 |
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| 分子式 | C16H23Cl2N3O2S | 运输 | 蓝冰 | |
| 分子量 | 392.34 | 别名 | H-1152 2HCl |
