CAS No.: 1402821-41-3
GV-58 Catalog No. CSN17796
Synonyms: GV-58
GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 μM for N-type/P-Q-type Ca2+ channel and 20-fold less potent CDK inhibitor activity.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Tarr TB, Lacomis D, et al. Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist. J Physiol. 2014 Aug 15;592(16):3687-96.
- [2] Tarr TB, Malick W, et al. Evaluation of a novel calcium channel agonist for therapeutic potential in Lambert-Eaton myasthenic syndrome. J Neurosci. 2013 Jun 19;33(25):10559-67.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1402821-41-3 | 储存条件 |
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| 分子式 | C18H26N6OS | 运输 | 蓝冰 | |
| 分子量 | 374.50 | 别名 | GV-58 |
