生物活性

• 描述Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT00000752	HIV Infections ... more >> Sinusitis Collapse <<	Phase 2	Withdrawn	-	United States, California ... more >> Univ of California / San Diego Treatment Ctr San Diego, California, United States, 921036325 Stanford at Kaiser / Kaiser Permanente Med Ctr San Francisco, California, United States, 94115 United States, New York Montefiore Drug Treatment Ctr / Bronx Municipal Hosp Bronx, New York, United States, 10461 Montefiore Family Health Ctr / Bronx Municipal Hosp Bronx, New York, United States, 10461 Samaritan Village Inc / Bronx Municipal Hosp Bronx, New York, United States, 10461 Jack Weiler Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10465 Montefiore Med Ctr / Bronx Municipal Hosp Bronx, New York, United States, 10467 Montefiore Med Ctr Adolescent AIDS Program Bronx, New York, United States, 10467 North Central Bronx Hosp / Bronx Municipal Hosp Bronx, New York, United States, 10467 United States, Pennsylvania Thomas Jefferson Univ Hosp Philadelphia, Pennsylvania, United States, 191075098 Collapse <<
  NCT02581397	Cough	Phase 3	Terminated(The study stopped b... more >>ecause after monitoring visits and data analysis we noticed a high number of protocol deviation that made impossible the results analysis.) Collapse <<	-	Brazil ... more >> L.A.L. Clínica Centro de Pesquisa e Desenvolvimento Ltda. Valinhos, São Paulo, Brazil, 13276-245 Collapse <<
  NCT03272295	Healthy Volunteers ... more >> Smoking Collapse <<	Not Applicable	Not yet recruiting	December 1, 2017	United Kingdom ... more >> Celerion Not yet recruiting Belfast, Northern Ireland, United Kingdom, BT9 6AD Contact: Johnston Stewart, MB    +44 (0) 28 90 554040 ext 4014    adrian.stewart@celerion.com    Principal Investigator: Johnstone Stewart, MB Collapse <<

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• 参考文献

• [1] Mimurai T, Yazaki K, et al. Hydroxyl radical scavenging effects of guaiacol used in traditional dental pulp sedation: reaction kinetic study. Biomed Res. 2005 Aug;26(4):139-45.

  [2] Rogers LE, Lyon GM Jr, Porter FS. Spot test for vanillylmandelic acid and other guaiacols in urine of patients with neuroblastoma. Am J Clin Pathol. 1972 Oct;58(4):383-7.