CAS No.: 937812-80-1
gamma-Secretase Modulators Catalog No. CSN18608
Synonyms: Amyloid-β production inhibitor;γ-Secretase Modulators;Amyloid-beta Production Inhibitor
gamma-Secretase modulators is an Amyloid-β production inhibitor, useful for Alzheimer's disease.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01196416 Recurrent Melanoma ... more >> Stage IV Skin Melanoma Collapse << Phase 1 Phase 2 Completed - United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Collapse << NCT01196416 - - Completed - - NCT02534480 Alzheimer's Disease Phase 1 Completed - United States, California ... more >> WCCT Cypress, California, United States, 90630 Collapse << - 更多
- 参考文献
- [1] Watahiki H, Yagishita S, et al. CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Aβ42-lowering γ-secretase modulators. Neurosci Lett. 2012 Sep 27;526(2):96-9.
- [2] Wagner SL, Tanzi RE, et al. Potential use of γ-secretase modulators in the treatment of Alzheimer disease. Arch Neurol. 2012 Oct;69(10):1255-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 937812-80-1 | 储存条件 |
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| 分子式 | C26H24F3N3O3 | 运输 | 蓝冰 | |
| 分子量 | 483.48 | 别名 | Amyloid-β production inhibitor;γ-Secretase Modulators;Amyloid-beta Production Inhibitor |
