CAS No.: 69123-90-6
Fiacitabine/非西他滨 Catalog No. CSN11011
Synonyms: NSC 382097;FIAC;FOAC
Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus (HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively.
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纯度 & 质量文件
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靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00000981 Cytomegalovirus Infections ... more >> HIV Infections Collapse << Phase 2 Completed - United States, Alabama ... more >> Univ of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Univ of California / San Diego Treatment Ctr San Diego, California, United States, 921036325 United States, Maryland Natl Institute of Health Bethesda, Maryland, United States, 20892 United States, Washington Univ of Washington / Madison Clinic Seattle, Washington, United States, 98122 Collapse << - 参考文献
- [1] Allaudeen HS, Descamps J, et al. Selective inhibition of DNA replication in herpes simplex virus infected cells by 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine. J Biol Chem. 1982 Oct 25;257(20):11879-82.
- [2] Lopez C, Watanabe KA, et al. 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent. Antimicrob Agents Chemother. 1980 May;17(5):803-6.
实验方案
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技术信息
| CAS号 | 69123-90-6 | 储存条件 |
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| 分子式 | C9H11FIN3O4 | 运输 | 蓝冰 | |
| 分子量 | 371.10 | 别名 | NSC 382097;FIAC;FOAC;DRG-0077;Fluoroiodoaracytidine. Fluorviodoaracytidine;非西他滨 |
