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CAS No.: 134381-21-8

Synonyms: BU-4061T;Aids-010837;环氧酶素

Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome.

规格	价格	促销价格	库存	数量

400-920-2911

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生物活性

描述Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome.
细胞研究

Cell Data

Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources
HEK293 cells	-	Function assay	2 h	Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to substrate addition measured after 10 mins by cell-based proteasome-Glo beta5 assay, IC50=0.026 μM	23540790
human DLD1 cells	-	Function assay	-	Inhibition of chymotrypsin-like activity of 20S proteasome in human DLD1 cells transfected with 4Ub-Luc gene using Succinyl-Leu-Leu-Val-Tyr-AMC as substrate after 6 hrs by spectrofluorometric analysis, IC50=0.006 μM	22206869
human LCL cells	-	Function assay	12 h	Inhibition of chymotrypsin-like activity of 20S proteasome beta2 in human LCL cells after 12 hrs, IC50=0.005 μM	20687609

实验方案

技术信息

CAS号	134381-21-8	储存条件	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C28H50N4O7	运输	蓝冰
分子量	554.72	别名	BU-4061T;Aids-010837;环氧酶素

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