CAS No.: 84294-96-2
Enoxacin Sesquihydrate/依诺沙星 倍半水合物 Catalog No. CSN16082
Synonyms: Enoxacin sesquihydrate;AT-2266 hydrate;CI-919 hydrate
Enoxacin Sesquihydrate is a broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea, working by inhibiting bacterial DNA gyrase and topoisomerase IV.
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- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02099240 Osteomyelitis Early Phase 1 Recruiting September 2019 United States, Kentucky ... more >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD 502-852-1148 jarami01@louisville.edu Contact: David Seligson, MD 502-852-0923 d0seli01@louisville.edu Sub-Investigator: Forest Arnold, DO Sub-Investigator: Timothy Wiemkwn, PhD Sub-Investigator: Robert Kelley, PhD Sub-Investigator: James Summersgill, PhD Sub-Investigator: Ruth Carrico, PhD Sub-Investigator: Julie Harting, PharmD Sub-Investigator: Paula Peyrani, MD Principal Investigator: David Seligson, MD Sub-Investigator: Craig Roberts, MD Principal Investigator: Julio Ramirez, MD Collapse << NCT02305342 - - Completed - Pakistan ... more >> Research facility ID ORG-001126 Karachi, Pakistan, 75190 Collapse << - 参考文献
- [1] Wijnands WJ, Vree TB, Van Herwaarden CL. Enoxacin decreases the clearance of theophylline in man. Br J Clin Pharmacol. 1985 Dec;20(6):583-8.
- [2] Chin NX, Neu HC. In vitro activity of enoxacin, a quinolone carboxylic acid, compared with those of norfloxacin, new beta-lactams, aminoglycosides, and trimethoprim. Antimicrob Agents Chemother. 1983 Nov;24(5):754-63.
- [3] Chin NX, Neu HC. In vitro activity of enoxacin, a quinolone carboxylic acid, compared with those of norfloxacin, new beta-lactams, aminoglycosides, and trimethoprim. Antimicrob Agents Chemother. 1983;24(5):754–763
- [4] Henwood JM, Monk JP. Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1988;36(1):32–66
- [5] Vracar TC, Zuo J, Park J, et al. Enoxacin and bis-enoxacin stimulate 4T1 murine breast cancer cells to release extracellular vesicles that inhibit osteoclastogenesis. Sci Rep. 2018;8(1):16182
- [6] Nishi K, Kato M, Sakurai S, Matsumoto A, Iwase Y, Yumita N. Enoxacin with UVA Irradiation Induces Apoptosis in the AsPC1 Human Pancreatic Cancer Cell Line Through ROS Generation. Anticancer Res. 2017;37(11):6211–6214
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技术信息
| CAS号 | 84294-96-2 | 储存条件 |
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| 分子式 | C30H40F2N8O9 | 运输 | 蓝冰 | |||
| 分子量 | 694.68 | 别名 | Enoxacin sesquihydrate;AT-2266 hydrate;CI-919 hydrate;Enoxacin Hydrate;依诺沙星倍半水合物 | |||
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动物实验配方 |
