CAS No.: 112093-28-4
Endoxifen (Z-isomer)/Z-因多昔芬 Catalog No. CSN17474
Synonyms: (Z)-Endoxifen;4-Hydroxy-N-desmethyltamoxifen;N-Desmethyl-4-hydroxytamoxifen
Endoxifen is the most important tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chae YJ, Lee KJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7.
- [2] Wu X, Subramaniam M, et al. Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen. Breast Cancer Res. 2011 Mar 10;13(2):R27.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 112093-28-4 | 储存条件 |
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| 分子式 | C25H27NO2 | 运输 | 蓝冰 | |
| 分子量 | 373.49 | 别名 | (Z)-Endoxifen;4-Hydroxy-N-desmethyltamoxifen;N-Desmethyl-4-hydroxytamoxifen;Z-因多昔芬 |
