CAS No.: 722533-56-4
Elacestrant Catalog No. CSN19762
Synonyms: RAD1901
Elacestrant is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities.
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- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02650817 Metastatic Breast Cancer Phase 1 Active, not recruiting February 2019 Belgium ... more >> Institut Jules Bordet Bruxelles, Belgium, 1000 UZ Leuven Campus Gasthuisberg Leuven, Belgium, 3000 Netherlands Vrije Universiteit Medisch Centrum (VUMC) Amsterdam, Netherlands Universitair Medisch Centrum Groningen (UMCG) Groningen, Netherlands Erasmus Medical Center Rotterdam, Netherlands Collapse << NCT02338349 Advanced ER+, HER2-Negative Br... more >>east Cancer Collapse << Phase 1 Active, not recruiting May 2019 United States, Massachusetts ... more >> Radius Pharmaceuticals, Inc. Waltham, Massachusetts, United States, 02451 Collapse << - 参考文献
- [1] Bihani T, Patel HK, et al. Elacestrant (RAD1901), a selective estrogen receptor degrader (SERD), has anti-tumor activity in multiple ER+ breast cancer patient-derived xenograft models. Clin Cancer Res. 2017 May 4. pii: clincanres.2561.2016.
- [2] Garner F, Shomali M, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56.
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技术信息
| CAS号 | 722533-56-4 | 储存条件 |
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| 分子式 | C30H38N2O2 | 运输 | 蓝冰 | |
| 分子量 | 458.63 | 别名 | RAD1901 |
