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CAS No.: 62-97-5

Diphenmanil methylsulfate Catalog No. CSN10833

Synonyms: Diphemanil mesylate;Diphemanil (methyl sulfate);NSC 41725

Diphemanil methylsulfate can bind the muscarinic M3 receptor and decrease secretory excretion of stomach acids and saliva and sweat, as well as works as a direct smooth muscle spasmolytic activity.

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技术信息

生物活性

描述Diphemanil Methylsulfate is a quaternary ammonium anticholinergic with both parasympatholytic and direct bronchial smooth muscle relaxing properties, has been found effective in the treatment of bronchial asthma^[3]. Serious undesirable cardiac side effects have been reported with treatment with diphemanil methylsulfate in premature babies or neonates^[4]. Oral diphemanil methylsulphate, absorption of the drug was slow (tmax = 2 to 4 h), the mean half-life was 8.35 h, and the amount of the drug recovered in urine within 48 h ranged from 0.6 to 7.4% of the administered dose^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.5673 mL
- 12.8367 mL
- 25.6734 mL
- 5 mM
- 0.5135 mL
- 2.5673 mL
- 5.1347 mL
- 10 mM
- 0.2567 mL
- 1.2837 mL
- 2.5673 mL

技术信息

CAS号

62-97-5

储存条件

粉末: Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H27NO4S

运输

蓝冰

分子量

389.51

别名

Diphemanil mesylate;Diphemanil (methyl sulfate);NSC 41725

溶解度

DMSO	24.0 mg/mL (61.6 mM)
Water	26.0 mg/mL (66.8 mM)
Ethanol	Insoluble

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