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CAS No.: 58-28-6
Synonyms: Desmethylimipramine;Norimipramine;EX-4355
Desipramine HCl is a dibenzazepine-derived tricyclic antidepressant which can selectively block reuptake of norepinephrine from the neural synapse, and also appear to impair serotonin transport.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01179828 | Low Back Pain | Phase 3 | Completed | - | Switzerland ... more >> Andreas Siegenthaler Dep. of Anesthesiolgy and Pain therapy, Bern University Hospital, Switzerland, 3010 Bern Collapse << |
NCT00704860 | Major Depression | Phase 4 | Completed | - | Canada, Ontario ... more >> University of Ottawa Institute of Mental Health Research Ottawa, Ontario, Canada, K1Z 7K4 Collapse << |
NCT00000241 | Substance-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> Friends Research Institute Los Angeles, California, United States, 90025 Collapse << |
实验方案
技术信息
CAS号 | 58-28-6 | 储存条件 |
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分子式 | C18H23ClN2 | 运输 | 蓝冰 | |||||
分子量 | 302.84 | 别名 | Desmethylimipramine;Norimipramine;EX-4355;G-35020;JB-8181;NSC-114901;Desipramine Hydrochloride;Norpramin;盐酸去甲咪嗪;盐酸地昔帕明 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01179828 | Low Back Pain | Phase 3 | Completed | - | Switzerland ... more >> Andreas Siegenthaler Dep. of Anesthesiolgy and Pain therapy, Bern University Hospital, Switzerland, 3010 Bern Collapse << |
NCT00704860 | Major Depression | Phase 4 | Completed | - | Canada, Ontario ... more >> University of Ottawa Institute of Mental Health Research Ottawa, Ontario, Canada, K1Z 7K4 Collapse << |
NCT00000241 | Substance-Related Disorders | Phase 2 | Completed | - | United States, California ... more >> Friends Research Institute Los Angeles, California, United States, 90025 Collapse << |
NCT00000217 | Cocaine-Related Disorders ... more >> Substance-Related Disorders Collapse << | Phase 2 | Completed | - | United States, Missouri ... more >> University of Kansas Kansas City, Missouri, United States, 64128 Collapse << |
NCT02191358 | - | - | Completed | - | United States, California ... more >> Dr. Michael Dao Garden Grove, California, United States, 92844 United States, Colorado Kaiser Permanente Colorado Denver, Colorado, United States, 80011 United States, Kentucky Gill Heart Institute Lexington, Kentucky, United States, 40508 United States, Maryland IRC Clinics Towson, Maryland, United States, 21204 United States, Massachusetts Internal Medicine & Cardiology Associates Fall River, Massachusetts, United States, 02720 Prima CARE Fall River, Massachusetts, United States, 02720 United States, Virginia Carilion Clinic Christiansburg, Virginia, United States, 24073 Collapse << |
NCT00000202 | Opioid-Related Disorders | Phase 2 | Completed | - | United States, Connecticut ... more >> VA Connecticut Healthcare System New Haven, Connecticut, United States, 06519 Collapse << |
NCT00964886 | Back Pain | Phase 2 | Completed | - | United States, California ... more >> VA San Diego Healthcare System, San Diego, CA San Diego, California, United States, 92161 Collapse << |
NCT00964886 | - | - | Completed | - | - |
NCT00018733 | Depression | Not Applicable | Completed | - | United States, Texas ... more >> South Texas Veterans Health Care System San Antonio, Texas, United States, 78229 Collapse << |
NCT00004390 | Pain Herpes Z... more >>oster Collapse << | Phase 3 | Completed | - | - |
NCT00220844 | Functional Dyspepsia | Not Applicable | Unknown | - | United States, Pennsylvania ... more >> Temple University School of Medicine Recruiting Philadelphia, Pennsylvania, United States, 19140 Contact: Henry P Parkman, MD 215-707-3431 henry.parkman@temple.edu Principal Investigator: Henry P Parkman, MD Collapse << |
NCT00000376 | Depression An... more >>xiety Disorders Personality Disorders Drug-resistant Depression Collapse << | Not Applicable | Completed | - | - |
NCT00000218 | Cocaine-Related Disorders ... more >> Substance-Related Disorders Collapse << | Phase 4 | Completed | - | United States, Missouri ... more >> University of Kansas Kansas City, Missouri, United States, 64128 Collapse << |
NCT00265291 | Major Depressive Disorder ... more >> Major Depression Unipolar Depression Collapse << | Phase 2 | Completed | - | United States, Florida ... more >> Center for Pharmacogenomics, University of Miami Miami, Florida, United States, 33136 Collapse << |
NCT00000212 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, New York ... more >> Columbia University New York, New York, United States, 10023 Collapse << |
NCT00018200 | Back Pain Sci... more >>atica Collapse << | Phase 2 | Completed | - | United States, California ... more >> VA San Diego Healthcare System, San Diego San Diego, California, United States, 92161 Collapse << |
NCT00006157 | Irritable Bowel Syndrome ... more >> Constipation Abdominal Pain Functional Colonic Diseases Collapse << | Phase 3 | Completed | - | United States, North Carolina ... more >> UNC Center for Functional GI Motility Disorders Chapel Hill, North Carolina, United States, 27599-7080 Canada, Ontario Centre for Addiction and Mental Health, Clark Site Toronto, Ontario, Canada, M5T 1R8 Collapse << |
NCT00000321 | Substance-Related Disorders | Phase 4 | Completed | - | United States, California ... more >> Friends Research Institute Los Angeles, California, United States, 90025 Collapse << |
NCT01265550 | GERD | Phase 3 | Completed | - | United States, Alabama ... more >> Birmingham VA Medical Center, Birmingham, AL Birmingham, Alabama, United States, 35233 United States, Arizona Southern Arizona VA Health Care System, Tucson, AZ Tucson, Arizona, United States, 85723 United States, California VA Loma Linda Healthcare System, Loma Linda, CA Loma Linda, California, United States, 92357 VA Long Beach Healthcare System, Long Beach, CA Long Beach, California, United States, 90822 United States, Connecticut VA Connecticut Healthcare System West Haven Campus, West Haven, CT West Haven, Connecticut, United States, 06516 United States, Maryland Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD Baltimore, Maryland, United States, 21201 United States, Massachusetts VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA Boston, Massachusetts, United States, 02130 United States, Michigan VA Ann Arbor Healthcare System, Ann Arbor, MI Ann Arbor, Michigan, United States, 48105 United States, Missouri Kansas City VA Medical Center, Kansas City, MO Kansas City, Missouri, United States, 64128 United States, New York Syracuse VA Medical Center, Syracuse, NY Syracuse, New York, United States, 13210 United States, North Carolina Durham VA Medical Center, Durham, NC Durham, North Carolina, United States, 27705 Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC Salisbury, North Carolina, United States, 28144 United States, Texas VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX Dallas, Texas, United States, 75216 Michael E. DeBakey VA Medical Center, Houston, TX Houston, Texas, United States, 77030 United States, Washington VA Puget Sound Health Care System Seattle Division, Seattle, WA Seattle, Washington, United States, 98108 Collapse << |
NCT00338962 | - | - | Completed | - | - |
NCT00166114 | Major Depressive Disorder | Phase 4 | Completed | - | United States, Georgia ... more >> Emory University School of Medicine Atlanta, Georgia, United States, 30322 Collapse << |
NCT01265550 | - | - | Completed | - | - |
NCT00338962 | Alcoholism De... more >>pression PTSD Collapse << | Phase 3 | Completed | - | United States, Connecticut ... more >> VA Connecticut Healthcare Systems West Haven, Connecticut, United States, 06516 Collapse << |
NCT00320632 | Depression | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts Mental Health Center Boston, Massachusetts, United States, 02115 Collapse << |
NCT00456014 | - | - | Completed | - | - |
NCT00166114 | - | - | Completed | - | - |
NCT00329147 | Depression | Phase 3 | Completed | - | United States, New Jersey ... more >> Neptune, New Jersey, United States, 07753 Collapse << |
NCT00000245 | Cocaine-Related Disorders ... more >> Substance-Related Disorders Collapse << | Phase 2 | Completed | - | United States, California ... more >> Friends Research Institute Los Angeles, California, United States, 90025 Collapse << |
NCT00500721 | Healthy | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Philadelphia, Pennsylvania, United States, 19148 Collapse << |
NCT00456014 | Depression | Not Applicable | Completed | - | United States, New York ... more >> Columbia University/New York State Psychiatric Institute New York, New York, United States, 10032 Collapse << |
NCT00366652 | Depression De... more >>pressive Disorder Depressive Disorder, Major Collapse << | Phase 3 | Completed | - | United States, New Jersey ... more >> Neptune, New Jersey, United States, 07753 Collapse << |
NCT01358968 | Cancer | Phase 1 | Completed | - | United States, Tennessee ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Memphis, Tennessee, United States, 38120 Collapse << |
NCT00913237 | Depression | Phase 1 | Completed | - | - |
NCT00000271 | Cocaine-Related Disorders ... more >> Substance-Related Disorders Collapse << | Phase 2 | Completed | - | United States, New York ... more >> Research Foundation for Mental Hygiene New York, New York, United States, 10032 Collapse << |
NCT00276068 | Vulvar Disease | Not Applicable | Completed | - | United States, New York ... more >> Strong Memorial Hospital Rochester, New York, United States, 14642 Collapse << |
NCT01153542 | In Development for Cystic Fibr... more >>osis Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> Covance CRU, Inc. Daytona Beach, Florida, United States, 32117 Collapse << |
NCT03726996 | Infantile Neuroaxonal Dystroph... more >>y Collapse << | Phase 4 | Not yet recruiting | November 30, 2020 | United States, North Carolina ... more >> Duke University Health Center Not yet recruiting Durham, North Carolina, United States, 27710 Contact: Janet Wootton, RN 919-668-4809 janet.wootton@duke.edu Collapse << |
NCT01415128 | Erectile Dysfunction | Phase 1 | Completed | - | - |
NCT02436031 | Sleep Apnea, Obstructive | Phase 2 | Completed | - | United States, Massachusetts ... more >> Sleep Disorders Research Program Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Collapse << |
NCT00913822 | Depression | Phase 1 | Completed | - | - |
NCT02436031 | - | - | Completed | - | - |
NCT02428478 | - | - | Completed | - | - |
NCT01411085 | Schizophrenia ... more >> Alcoholism Dual Diagnosis Collapse << | Phase 2 | Completed | - | United States, Massachusetts ... more >> University of Massachusetts Medical School Worcester, Massachusetts, United States, 01605 United States, Michigan Michigan State University / Cherry Street Health Services Grand Rapids, Michigan, United States, 49503 United States, New Hampshire Dartmouth Medical School Lebanon, New Hampshire, United States, 03756 United States, South Carolina University of South Carolina School of Medicine Columbia, South Carolina, United States, 29203 Collapse << |
NCT02428478 | Sleep Apnea, Obstructive | Phase 2 | Completed | - | United States, Massachusetts ... more >> Sleep Disorders Research Program Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Collapse << |
NCT01411085 | - | - | Completed | - | - |
NCT00880594 | Irritable Bowel Syndrome | Not Applicable | Active, not recruiting | May 2019 | United States, Missouri ... more >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Collapse << |
NCT02273466 | Healthy | Phase 1 | Completed | - | - |
NCT01478568 | Pharmacokinetics of Mirabegron... more >> Healthy Subjects Collapse << | Phase 1 | Completed | - | France ... more >> SGS Aster Paris, France, 75015 Collapse << |
NCT01899326 | DS Stage I Plasma Cell Myeloma... more >> DS Stage II Plasma Cell Myeloma DS Stage III Plasma Cell Myeloma Refractory Plasma Cell Myeloma Collapse << | Not Applicable | Unknown | - | United States, New York ... more >> Albert Einstein College of Medicine Bronx, New York, United States, 10461 Collapse << |
NCT00914004 | Depression | Phase 1 | Completed | - | - |
NCT01358968 | - | - | Completed | - | - |
NCT00913809 | Depression | Phase 1 | Completed | - | - |
NCT00990691 | Rett Syndrome | Phase 2 | Completed | - | France ... more >> Assistance Publique - Hopitaux de Marseille Marseille, France Collapse << |
NCT01719861 | - | - | Terminated(Lack of efficacy) | - | - |
NCT03548454 | Chronic Pain | Phase 4 | Recruiting | July 31, 2020 | United States, California ... more >> Stanford Pain Management Center Recruiting Redwood City, California, United States, 94063 Contact: Vafi Salmasi, MD. 650-725-0246 vsalmasi@stanford.edu Collapse << |
NCT01719861 | Small Cell Lung Cancer (SCLC) ... more >> Neuroendocrine Tumors Collapse << | Phase 2 | Terminated(Lack of efficacy) | - | United States, California ... more >> Stanford University Cancer Institute Stanford, California, United States, 94305 Collapse << |
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