CAS No.: 56-47-3
Deoxycorticosterone Acetate/乙酸去氧皮质酮 Catalog No. CSN10770
Synonyms: 11-Deoxycorticosterone acetate;DOC acetate;Cortexone acetate
Deoxycorticosterone acetate is a corticosteroid hormone which can induce hypertension dependent on altered regulation of central pressor mechanisms including the brain renin-angiotensin system.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01186484 Prostatic Neoplasms Phase 1 Completed - Japan ... more >> Fukuoka, Japan Kashiwa, Japan Koto-Ku, Japan Sunto, Japan Yokohama, Japan Collapse << NCT03082339 - - Recruiting March 31, 2018 Germany ... more >> University Giessen Recruiting Gießen, Germany, 35394 Contact: Matthias Hecker, MD Neurologische Klinik Bad Salzhausen Recruiting Nidda, Germany, 63667 Contact: Dirk Bandorski, MD Contact: Jens Allendörfer, MD Collapse << - 参考文献
- [1] Borde P, Mohan M, et al. Effect of myricetin on deoxycorticosterone acetate (DOCA)-salt-hypertensive rats. Nat Prod Res. 2011 Sep;25(16):1549-59.
- [2] Underwood KA, McCutcheon NB, et al. The effects of fludrocortisone acetate and deoxycorticosterone acetate on salt appetite in mice. Physiol Behav. 1993 Oct;54(4):671-5.
- [3] Jackson D, Connolly K, Batacan R, Ryan K, Vella R, Fenning A. (-)-Epicatechin Reduces Blood Pressure and Improves Left Ventricular Function and Compliance in Deoxycorticosterone Acetate-Salt Hypertensive Rats. Molecules. 2018 Jun 22;23(7):1511.
- [4] Ito H, Majima M, Nakajima S, Hayashi I, Katori M, Izumi T. Effect of prolonged administration of a urinary kinase inhibitor, ebelactone B on the development of deoxycorticosterone acetate-salt hypertension in rats. Br J Pharmacol. 1999 Feb;126(3):613-20.
- [5] Sonnenberg H. Proximal and distal tubular function in salt-deprived and in salt-loaded deoxycorticosterone acetate-escaped rats. J Clin Invest. 1973 Feb;52(2):263-72.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 56-47-3 | 储存条件 |
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| 分子式 | C23H32O4 | 运输 | 蓝冰 | |||||||||||||
| 分子量 | 372.50 | 别名 | 11-Deoxycorticosterone acetate;DOC acetate;Cortexone acetate;Deoxycorticosterone Acetate;DOCA;Percotol;醋酸去氧皮质酮 | |||||||||||||
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