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CAS No.: 65236-62-6

Dehydrocrenatidine Catalog No. CSN14154

Synonyms: Kumujian G;O-Methylpicrasidine I;TOP-3

Dehydrocrenatidine, a natural product isolated and purified from the barks of Picrasma quassioides, is a JAK-specific inhibitor, which inhibits JAK2-JH1 kinase activity in vitro , represses constitutively activated JAK2 and STAT3, as well as interleukin-6-, interferon-α-, and interferon-γ-stimulated JAK activity, and STAT phosphorylation, and suppresses STAT3 and STAT1 downstream gene expression.

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描述Dehydrocrenatidine, a natural product isolated and purified from the barks of Picrasma quassioides, is a JAK-specific inhibitor, which inhibits JAK2-JH1 kinase activity in vitro , represses constitutively activated JAK2 and STAT3, as well as interleukin-6-, interferon-α-, and interferon-γ-stimulated JAK activity, and STAT phosphorylation, and suppresses STAT3 and STAT1 downstream gene expression.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.9326 mL
- 19.6631 mL
- 39.3261 mL
- 5 mM
- 0.7865 mL
- 3.9326 mL
- 7.8652 mL
- 10 mM
- 0.3933 mL
- 1.9663 mL
- 3.9326 mL

技术信息

CAS号	65236-62-6	储存条件	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C15H14N2O2	运输	蓝冰
分子量	254.28	别名	Kumujian G;O-Methylpicrasidine I;TOP-3

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