CAS No.: 1375465-09-0
CNX-2006 Catalog No. CSN17167
CNX-2006 is an irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Mizuuchi H, Suda K, et al. Oncogene swap as a novel mechanism of acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor in lung cancer. Cancer Sci. 2016 Apr;107(4):461-8.
- [2] Galvani E, Sun J, et al. NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor. Oncotarget. 2015 Dec 15;6(40):42717-32.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1375465-09-0 | 储存条件 |
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| 分子式 | C26H27F4N7O2 | 运输 | 蓝冰 | |
| 分子量 | 545.53 | 别名 |
