生物活性

• 描述Cloxacillin is a semisynthetic antibiotic that belongs to the group of the isoxazolylpenicillins and is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT01582360	-	-	Unknown	January 2018	Norway ... more >> Oslo University Hospital Recruiting Oslo, Norway Principal Investigator: Elin Helset, MD PhD          Principal Investigator: Jan Fr Bugge, MD PhD          Principal Investigator: Hilde Ma Sporsem, cand pharm          Principal Investigator: Yvonne Lao, cand pharm          Principal Investigator: Kirsti Andersson, MD Collapse <<
  NCT02099240	Osteomyelitis	Early Phase 1	Recruiting	September 2019	United States, Kentucky ... more >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD    502-852-1148    jarami01@louisville.edu    Contact: David Seligson, MD    502-852-0923    d0seli01@louisville.edu    Sub-Investigator: Forest Arnold, DO          Sub-Investigator: Timothy Wiemkwn, PhD          Sub-Investigator: Robert Kelley, PhD          Sub-Investigator: James Summersgill, PhD          Sub-Investigator: Ruth Carrico, PhD          Sub-Investigator: Julie Harting, PharmD          Sub-Investigator: Paula Peyrani, MD          Principal Investigator: David Seligson, MD          Sub-Investigator: Craig Roberts, MD          Principal Investigator: Julio Ramirez, MD Collapse <<
  NCT01971762	-	-	Completed	-	Spain ... more >> Hospital de Puerto Real Puerto Real, Cádiz, Spain Hospital Costa del Sol Marbella, Málaga, Spain Hospital de Torrecárdenas Almería, Spain Hospital de barcelona - SCIAS Barcelona, Spain Hospital de Cruces Bilbao, Spain Hospital Puerta del Mar Cádiz, Spain Hospital Reina Sofía Córdoba, Spain Hospital Virgen de las Nieves Granada, Spain Hospital Juan Ramón Jiménez Huelva, Spain Hospital de San Pedro Logroño, Spain Hospital de la Arrixaca Murcia, Spain Hospital Carlos Haya Málaga, Spain Hospital Virgen de la Victoria Málaga, Spain Hospital de Valdecillas Santander, Spain Hospital Universitario Virgen de la Macarena Sevilla, Spain Hospital Virgen de Valme Sevilla, Spain Collapse <<

• 更多
• 参考文献

• [1] Lemaire S, Van Bambeke F, et al. Role of acidic pH in the susceptibility of intraphagocytic methicillin-resistant Staphylococcus aureus strains to meropenem and cloxacillin. Antimicrob Agents Chemother. 2007 May;51(5):1627-32.

  [2] Kheadr E, Dabour N, et al. Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. Antimicrob Agents Chemother. 2007 Jan;51(1):169-74. Epub 2006 Oct 23.