CAS No.: 180384-56-9
Clazosentan Catalog No. CSN19760
Synonyms: AXV-343434;VML-588;Ro 61-1790
Clazosentan is a potent endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury.
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纯度 & 质量文件
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靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00111085 Aneurysmal Subarachnoid Hemorr... more >>hage Collapse << Phase 2 Completed - United States, Illinois ... more >> Dr. Giuseppe Lanzino Peoria, Illinois, United States United States, Indiana Dr. Horner Indianapolis, Indiana, United States United States, Maryland Dr. Aldrich Baltimore, Maryland, United States United States, Massachusetts Dr. Ogilvy Boston, Massachusetts, United States United States, Ohio Dr. Zuccarello Cincinnati, Ohio, United States Dr. Woo Cleveland, Ohio, United States United States, Pennsylvania Dr. Rosenwasser Philadelphia, Pennsylvania, United States Dr. Zager Philadelphia, Pennsylvania, United States United States, Texas Dr. George A. Lopez Houston, Texas, United States United States, Virginia Dr. Bullock Richmond, Virginia, United States Canada, Alberta Dr. Wong Calgary, Alberta, Canada Dr. Findlay Edmonton, Alberta, Canada Canada, British Columbia Dr. Redekop Vancouver, British Columbia, Canada Canada, Ontario Dr. Ferguson Toronto, Ontario, Canada Canada, Quebec Dr. Bojanowski Montreal, Quebec, Canada Canada Dr. Fleetwood Halifax, Nova Scotia, Canada Collapse << NCT00558311 Aneurysmal Subarachnoid Hemorr... more >>hage Collapse << Phase 3 Completed - - NCT03596294 Healthy Subjects Phase 1 Completed - Netherlands ... more >> QPS Netherlands B.V. Groningen, Netherlands, 9713 GZ Collapse << - 更多
- 参考文献
- [1] Fujimura M, Joo JY, et al. Preventive Effect of Clazosentan against Cerebral Vasospasm after Clipping Surgery for Aneurysmal Subarachnoid Hemorrhage in Japanese and Korean Patients. Cerebrovasc Dis. 2017 May 3;44(1-2):59-67.
- [2] Wong GK, Poon WS. Clazosentan for patients with subarachnoid haemorrhage: lessons learned. Lancet Neurol. 2011 Oct;10(10):871; author reply 871-2.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 180384-56-9 | 储存条件 |
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| 分子式 | C25H23N9O6S | 运输 | 蓝冰 | |
| 分子量 | 577.57 | 别名 | AXV-343434;VML-588;Ro 61-1790;AXV-034343 |
