CAS No.: 847728-01-2
CJ-42794 Catalog No. CSN13150
Synonyms: CJ-042794;RQ-00015986;RQ-15986
CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Murase A, Taniguchi Y, et al. In vitro pharmacological characterization of CJ-042794, a novel, potent, and selective prostaglandin EP(4) receptor antagonist. Life Sci. 2008 Jan 16;82(3-4):226-32.
- [2] Hatazawa R, Tanaka A, et al. Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors. Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G788-97.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 847728-01-2 | 储存条件 |
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| 分子式 | C22H17ClFNO4 | 运输 | 蓝冰 | |
| 分子量 | 413.83 | 别名 | CJ-042794;RQ-00015986;RQ-15986 |
