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CAS No.: 104-46-1

cis-Anethol/茴香脑 Catalog No. CSN10312

Synonyms: Anise camphor;p-Propenylanisole;Isoestragole

Anethole is a natural aromatic compound isolated and purified from the fruits of Foeniculum vulgare, and is widely used as a flavoring substance. Anethole has antispasmodic, cardiovascular, and gastroprotective effects.

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技术信息

生物活性

描述Anethole, existing in fennel, is a major component of foeniculum vulgare (fennel) essential oil, widely used in folk medicine^[1] . In vitro studies, it was found that anethole could inhibit the proliferation, growth and migration of PC-3 cells^[1] . In addition, anethole also has the ability of suppressing the adipogenic differentiation of human mesenchymal stem cells (hMSCs) through regulating activities of specific enzymes^[2] . In vivo studies, anethole contributed to the improvement of neuropathic pain in mice induced by chronic constriction injury (CCI) ^[3] . Besides this, anethole could also reduce inflammation and the level of cytokines and nitric oxide in rats with adjuvant-induced arthritis^[1] .
参考文献

[1] Elkady AI. Anethole Inhibits the Proliferation of Human Prostate Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis. Anticancer Agents Med Chem. 2018;18(2):216-236.
[2] Rhee YH, Moon JH, et al. mTOR and ROS regulation by anethole on adipogenic differentiation in human mesenchymal stem cells. BMC Cell Biol. 2018;19(1):12.
[3] Wang B, Zhang G, et al. Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice. Neurochem Res. 2018;43(12):2404-2422.
[4] Ritter AMV, Hernandes L, et al. Anethole reduces inflammation and joint damage in rats with adjuvant-induced arthritis. Inflamm Res. 2017;66(8):725-737.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 6.7476 mL
- 33.7382 mL
- 67.4764 mL
- 5 mM
- 1.3495 mL
- 6.7476 mL
- 13.4953 mL
- 10 mM
- 0.6748 mL
- 3.3738 mL
- 6.7476 mL

技术信息

CAS号

104-46-1

储存条件

粉末: Sealed in dry,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C10H12O

运输

蓝冰

分子量

148.20

别名

Anise camphor;p-Propenylanisole;Isoestragole;Anethol;p-Anthole;AI3-00380;NSC-4018;茴香脑

溶解度

DMSO	98.0 mg/mL (661.3 mM)

动物实验配方

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