|2-(3-苯基丙烯酰胺)乙酸|CsnPharm

CAS No.: 16534-24-0

Cinnamoylglycine/2-(3-苯基丙烯酰胺)乙酸 Catalog No. CSN26907

Synonyms: 肉桂酰甘氨酸

Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment[1].

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生物活性

描述Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment^[1]. Hazards models also suggested an association between low cinnamoylglycine clearance and risk of dialysis, but statistical analyses did not exclude the null hypothesis^[2]. The pattern of metabolites found in urine is significantly changed following Formaldehyde inhalation, and hippuric acid and cinnamoylglycine might represent potential biomarker candidates for FA exposure^[3]. Discrimination of O. volvulus infections from controls or individuals suffering from multiple infections was improved by the measurement of additional metabolites, e.g. cinnamoylglycine^[4].
参考文献

[1] Obrenovich ME, Tima M, Polinkovsky A, Zhang R, Emancipator SN, Donskey CJ. Targeted Metabolomics Analysis Identifies Intestinal Microbiota-Derived Urinary Biomarkers of Colonization Resistance in Antibiotic-Treated Mice. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00477-17
[2] Suchy-Dicey AM, Laha T, Hoofnagle A, Newitt R, Sirich TL, Meyer TW, Thummel KE, Yanez ND, Himmelfarb J, Weiss NS, Kestenbaum BR. Tubular Secretion in CKD. J Am Soc Nephrol. 2016 Jul;27(7):2148-55
[3] Zhang J, Sun R, Chen Y, Tan K, Wei H, Yin L, Pu Y. Small molecule metabolite biomarker candidates in urine from mice exposed to formaldehyde. Int J Mol Sci. 2014 Sep 17;15(9):16458-68
[4] Wewer V, Peisker H, Gutbrod K, Al-Bahra M, Menche D, Amambo NG, Fombad FF, Njouendou AJ, Pfarr K, Wanji S, Hoerauf A, Dörmann P. Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon. Parasit Vectors. 2021 Aug 11;14(1):397

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.8731 mL
- 24.3653 mL
- 48.7306 mL
- 5 mM
- 0.9746 mL
- 4.8731 mL
- 9.7461 mL
- 10 mM
- 0.4873 mL
- 2.4365 mL
- 4.8731 mL

技术信息

CAS号	16534-24-0	储存条件	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C11H11NO3	运输	蓝冰
分子量	205.21	别名	肉桂酰甘氨酸

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Cinnamoylglycine/2-(3-苯基丙烯酰胺)乙酸 Catalog No. CSN26907

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