CAS No.: 1262849-73-9
CCT241533 Catalog No. CSN17641
Synonyms: Cct241533
CCT241533 is a potent serine/threonine checkpoint kinase (Chk2) inhibitor with IC50 of 3 nM and shows minimal cross-reactivity against a panel of kinases at 1 μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Anderson VE, Walton MI, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 2011 Jan 15;71(2):463-72.
- [2] Caldwell JJ, Welsh EJ, et al. Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. J Med Chem. 2011 Jan 27;54(2):580-90.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1262849-73-9 | 储存条件 |
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| 分子式 | C23H27FN4O4 | 运输 | 蓝冰 | |
| 分子量 | 442.48 | 别名 | Cct241533 |
