CAS No.: 289715-28-2
CB 300919 Catalog No. CSN18183
Synonyms: UNII-55I8ETE76Y
CB-300919 is a water-soluble analogue of CB30865, a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt), and has a continuous exposure(96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Lockman JW, Murphy BR, et al. Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino] -N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt). J Med Chem. 2010 Dec 23;53(24):8734-46.
- [2] Bavetsias V, Skelton LA, et al. The design and synthesis of water-soluble analogues of CB30865, a quinazolin-4-one-based antitumor agent. J Med Chem. 2002 Aug 15;45(17):3692-702.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 289715-28-2 | 储存条件 |
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| 分子式 | C32H34ClN7O2 | 运输 | 蓝冰 | |
| 分子量 | 584.11 | 别名 | UNII-55I8ETE76Y |
