CAS No.: 145040-37-5
Candesartan cilexetil/坎地沙坦酯 Catalog No. CSN12553
Synonyms: TCV-116;Candesartan M1 Cilexetil;Candesartan cilexetil
Candesartan Cilexetil is a benzimidazole-derived and competitive AT1 inhibitor with IC50 value of 0.26 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 Angiotensin Receptor
IC50:0.26nM- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00319202 Glucose Intolerance ... more >> Obesity Collapse << Phase 4 Terminated(Difficulties in com... more >>pleting the required sample size) Collapse << - Colombia ... more >> Fundación Cardiovascular de Colombia Floridablanca, Santander, Colombia, 10000 Collapse << NCT01062451 Methamphetamine Dependence ... more >> Methamphetamine Abuse Substance Abuse Collapse << Phase 1 Active, not recruiting December 2018 United States, Texas ... more >> Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 Collapse << NCT00526279 - - Completed - Korea, Republic of ... more >> Research Site Seoul, Jongro-gu, Korea, Republic of Research Site Seoul, Kangnam-gu, Korea, Republic of Research Site Seoul, Songpa-gu, Korea, Republic of Collapse << - 更多
- 参考文献
- [1] Shirai K, Watanabe K, et al. Effects of angiotensin-II receptor blocker candesartan cilexetil in rats with dilated cardiomyopathy. Mol Cell Biochem. 2005 Jan;269(1-2):137-42.
- [2] See S, Stirling AL. Candesartan cilexetil: an angiotensin II-receptor blocker. Am J Health Syst Pharm. 2000 Apr 15;57(8):739-46.
- [3] Féghali RE, Nisse-Durgeat S, Asmar R. Effect of candesartan cilexetil on diabetic and non-diabetic hypertensive patients: meta-analysis of five randomized double-blind clinical trials. Vasc Health Risk Manag. 2007;3(1):165-71. PMID: 17583187; PMCID: PMC1994048.
- [4] Easthope SE, Jarvis B. Candesartan cilexetil: an update of its use in essential hypertension. Drugs. 2002;62(8):1253-87. doi: 10.2165/00003495-200262080-00016. PMID: 12010090.
- [5] Inada Y, Ojima M, Kanagawa R, Misumi Y, Nishikawa K, Naka T. Pharmacologic properties of candesartan cilexetil--possible mechanisms of long-acting antihypertensive action. J Hum Hypertens. 1999 Jan;13 Suppl 1:S75-80. doi: 10.1038/sj.jhh.1000749. PMID: 10076925.
- [6] Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, Michelson EL, Olofsson B, Ostergren J, Yusuf S, Pocock S; CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362(9386):759-66. doi: 10.1016/s0140-6736(03)14282-1. Erratum in: Lancet. 2009 Nov 21-2009 Nov 27;(9703):1744. PMID: 13678868.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 145040-37-5 | 储存条件 |
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| 分子式 | C33H34N6O6 | 运输 | 蓝冰 | |||||||
| 分子量 | 610.66 | 别名 | TCV-116;Candesartan M1 Cilexetil;Candesartan cilexetil;坎地沙坦酯;坎地沙坦西来替昔酯 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00319202 | Glucose Intolerance ... more >> Obesity Collapse << | Phase 4 | Terminated(Difficulties in com... more >>pleting the required sample size) Collapse << | - | Colombia ... more >> Fundación Cardiovascular de Colombia Floridablanca, Santander, Colombia, 10000 Collapse << |
| NCT01062451 | Methamphetamine Dependence ... more >> Methamphetamine Abuse Substance Abuse Collapse << | Phase 1 | Active, not recruiting | December 2018 | United States, Texas ... more >> Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 Collapse << |
| NCT00526279 | - | - | Completed | - | Korea, Republic of ... more >> Research Site Seoul, Jongro-gu, Korea, Republic of Research Site Seoul, Kangnam-gu, Korea, Republic of Research Site Seoul, Songpa-gu, Korea, Republic of Collapse << |
| NCT00802542 | - | - | Completed | - | Latvia ... more >> Research site Daugavpils, Latvia Research site Jelgava, Latvia Research site Liepaja, Latvia Research Site Riga, Latvia Collapse << |
| NCT00564057 | HIV Infections ... more >> Hypertension Collapse << | Phase 4 | Unknown | September 2009 | Italy ... more >> University of Insubria, Department of Clinical Medicine Recruiting Varese, Italy, 21100 Collapse << |
| NCT00644475 | Essential Hypertension | Phase 3 | Unknown | March 2009 | Italy ... more >> University of Pavia Recruiting Pavia, Italy, 27100 Contact: Giuseppe Derosa, MD +39 0382 502614 giuseppe.derosa@unipv.it Contact: Roberto Fogari, MD +39 0382 526217 r.fogari@unipv.it Principal Investigator: Giuseppe Derosa, MD Collapse << |
| NCT00150631 | Hypertension | Phase 3 | Unknown | December 2014 | Denmark ... more >> Karin Skov Aarhus, Denmark, 8000 Collapse << |
| NCT01766505 | Hypertension | Phase 4 | Terminated(lack of the subject... more >>s) Collapse << | - | Korea, Republic of ... more >> Chunbuk National University Hospital Chonju, Korea, Republic of, 561-712 Presbyterian Medical Center Chunju, Korea, Republic of, 560-750 Chungnam national university hospital Daejeon, Korea, Republic of, 301-721 The catholic university of Korea, Daejeon st. Mary's Hospital Daejeon, Korea, Republic of, 301-723 Eulji University Hospital Daejeon, Korea, Republic of, 302-799 Konyang university hospital Daejon, Korea, Republic of, 302-718 Chunnam National University Hospital Gwangju, Korea, Republic of, 501-757 Kwangju Christian Hospital Gwangju, Korea, Republic of, 503-715 ST.Carollo hospital Suncheon, Korea, Republic of, 540-719 Collapse << |
| NCT01682564 | Hypertension ... more >>Congestive Heart Failure Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Inje university pusan hospital Busan, Busanjin-gu Gaegum-dong, Korea, Republic of, 614-735 Gyeongsang national university hospital Jinju, Chiram-dong, Korea, Republic of, 660-702 Daegu fatima hospital Daegu, Dong-gu Sinam-dong, Korea, Republic of, 701-724 Daedong hospital Busan, Dongnae-gu Myeongnyun-dong, Korea, Republic of, 607-711 Inje university haeundae paik hospital Busan, Haeundae-gu Heaundae-ro 875, Korea, Republic of, 612-030 Maryknoll medical center Busan, Jung-gu Daecheong-dong, Korea, Republic of, 600-730 Keimyung university dongsan medical center Daegu, Jung-gu Dongsan-dong, Korea, Republic of, 700-712 Kyungpook national university hospital Daegu, Jung-gu Samdeok-dong, Korea, Republic of, 700-721 Samsung changwon hospital Changwon, Masanhoiwon-gu Hapseong-dong 50, Korea, Republic of, 630-723 Yeungnam university medical center Daegu, Nam-gu Daemyeong-dong, Korea, Republic of, 705-717 Daegu catholic univ. medical center Daegu, Nam-gu Daemyung-dong, Korea, Republic of, 705-718 Kosin university gospel hospital Busan, Seo-gu Amnam-dong, Korea, Republic of, 602-702 Dong-A university medical center Busan, Seo-gu Dongdaesin-dong, Korea, Republic of, 602-715 Dongguk university gyeongju hospital Gyeongju, Seokjang-dong, Korea, Republic of, 780-350 Collapse << |
| NCT01303783 | Hypertension, Essential | Phase 2 | Completed | - | - |
| NCT00459771 | Breast Cancer | Phase 3 | Completed | - | Netherlands ... more >> Medisch Centrum Alkmaar Alkmaar, Netherlands Flevoziekenhuis Almere, Netherlands The Netherlands Cancer Institute Amsterdam, Netherlands, 1066 CX Onze Lieve Vrouwe Gasthuis Amsterdam, Netherlands Slotervaart Hospital Amsterdam, Netherlands Wilhelmina Ziekenhuis Assen, Netherlands Jeroen Bosch Hospital Den Bosch, Netherlands Deventer Ziekenhuis Deventer, Netherlands Medisch Spectrum Twente Enschede, Netherlands Martini Ziekenhuis Groningen, Netherlands University Medical Center Groningen Groningen, Netherlands Ziekenhuis de Tjongerschans Heerenveen, Netherlands Medisch Centrum Leeuwarden Leeuwarden, Netherlands Antonius Ziekenhuis Nieuwegein, Netherlands Canisius-Wilhelmina Hospital Nijmegen, Netherlands UMC St. Radboud Nijmegen, Netherlands VieCuri Medisch Centrum voor Noord-Limburg Venlo, Netherlands Streekziekenhuis Koningin Beatrix Winterswijk, Netherlands Isala Klinieken Zwolle, Netherlands Collapse << |
| NCT00232882 | Hypertension | Phase 4 | Completed | - | Canada, Quebec ... more >> Institut de Recherches Cliniques de Montréal Montréal, Quebec, Canada, H2W 1R7 Collapse << |
| NCT00884663 | Migraine Without Aura ... more >> Migraine With Aura Chronic Migraine Collapse << | Phase 2 Phase 3 | Completed | - | Norway ... more >> Norwegian National Headache Centre, St. Olavs University Hospital Trondheim, Norway, 7489 Collapse << |
| NCT02064556 | Hypertension | Phase 1 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Songpa-gu, Korea, Republic of Collapse << |
| NCT00244634 | Pediatric Hypertension | Phase 3 | Completed | - | - |
| NCT02521246 | Essential Arterial Hypertensio... more >>n Collapse << | Phase 3 | Withdrawn(Sponsor decision) | August 2017 | - |
| NCT02707224 | Healthy | Phase 1 | Completed | - | - |
| NCT02609711 | Healthy Male Subjects | Phase 1 | Unknown | - | Korea, Republic of ... more >> Inha Univ. Hospital Incheon, Korea, Republic of Collapse << |
| NCT02079506 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Chungnam National University Hospital Jung-gu, Daejeon, Korea, Republic of, 301-721 Collapse << |
| NCT02651870 | Hypertension | Phase 3 | Unknown | February 2016 | Korea, Republic of ... more >> Severance Hospital Recruiting Seoul, Korea, Republic of Contact: Dong-Hoon Choi, M.D., Ph.D Principal Investigator: Dong-Hoon Choi, M.D, Ph.D Collapse << |
| NCT00282178 | Hypertension ... more >>Obesity Collapse << | Phase 2 | Completed | - | Sweden ... more >> Umeå University Hospital Umeå, Sweden, SE-90185 Collapse << |
| NCT02521233 | Essential Arterial Hypertensio... more >>n Collapse << | Phase 3 | Withdrawn(Sponsor decision) | August 2017 | - |
| NCT00608153 | - | - | Completed | - | - |
| NCT01135212 | Hypertension | Phase 3 | Completed | - | Korea, Republic of ... more >> KyungPook National University Hospital Daegu, Korea, Republic of, 110-750 Collapse << |
| NCT00244595 | Hypertension | Phase 3 | Completed | - | - |
| NCT00607633 | - | - | Completed | - | - |
| NCT01152567 | - | - | Completed | - | - |
| NCT00125463 | Hypertension ... more >>Cardiovascular Diseases Collapse << | Phase 3 | Unknown | - | Japan ... more >> Kyoto University Kyoto, Yoshidakonoe-cho, Sakyo-ku, Kyoto, Japan, 606-8501 Collapse << |
| NCT03688633 | Peripheral Neuropathy | Phase 2 | Not yet recruiting | June 1, 2021 | France ... more >> CHU Limoges Not yet recruiting Limoges, France, 87042 Contact: Laurent Magy, MD 05 55 05 65 68 laurent.magy@unilim.fr Collapse << |
| NCT00573742 | - | - | Completed | - | Romania ... more >> Research Site Bacau, Romania Research Site Braila, Romania Research Site Brasov, Romania Research Site Bucuresti, Romania Research Site Cluj, Romania Research Site Constanta, Romania Research Site Craiova, Romania Research Site Galati, Romania Research Site Ghiroda, Romania Research Site Iasi, Romania Research Site Lugoj, Romania Research Site Oradea, Romania Research Site Pitesti, Romania Research Site Ploiesti, Romania Research Site Sibiu, Romania Research Site Timisoara, Romania Collapse << |
| NCT02261116 | Healthy | Phase 4 | Completed | - | - |
| NCT00184587 | Cluster Headache | Phase 2 | Completed | - | Norway ... more >> Norwegian National Headache Centre St.Olavs Hospital Trondheim, Norway, 7006 Collapse << |
| NCT00905333 | Healthy | Phase 1 | Completed | - | Brazil ... more >> Research Site Itatiba, SP, Brazil Research Site Americana, Brazil Collapse << |
| NCT00679484 | Chronic Heart Failure ... more >> High Blood B-type (or Brain) Natriuretic Peptide (BNP) Level Collapse << | Phase 3 | Terminated(Lack of subject rec... more >>ruitment) Collapse << | - | France ... more >> Bron, France Cedex, France Cholet, France Langres, France Mannheim, France Pontoise, France Roubaix, France Germany Bad Nauheim, Germany Berlin, Germany Lambrecht, Germany Netherlands Ad Delft, Netherlands Collapse << |
| NCT02548286 | Hypertension | Phase 1 | Completed | - | Korea, Republic of ... more >> Chungnam National University Hospital Daejeon, Jung-gu, Korea, Republic of Collapse << |
| NCT00108706 | Cerebrovascular Accident ... more >> Acute Stroke Collapse << | Phase 4 | Unknown | - | United Kingdom ... more >> Sunderland Royal Hospital Sunderland, Tyne and Wear, United Kingdom, SR4 7TP Collapse << |
| NCT02186496 | Hypertension | Phase 1 | Completed | - | Korea, Republic of ... more >> Chungnam National University Hospital Daejeon, Chungcheongbuk-do, Korea, Republic of, 301-721 Collapse << |
| NCT03231982 | Hypertension | Phase 4 | Recruiting | May 31, 2019 | Korea, Republic of ... more >> Yonsei University Severance Cardiovascular Hospital Recruiting Seoul, Korea, Republic of Contact: Donghoon Choi, M.D., Ph.D. 82-2-2228-8200 cdhlyj@yuhs.ac Collapse << |
| NCT00775814 | Obesity Hyper... more >>tension Collapse << | Phase 4 | Completed | - | Germany ... more >> Bad Dürrheim, Baden-Württemberg, Germany Balingen, Baden-Württemberg, Germany Deggingen, Baden-Württemberg, Germany Rottweil, Baden-Württemberg, Germany Spaichingen, Baden-Württemberg, Germany Ingolstadt, Bayern, Germany München, Bayern, Germany Passau, Bayern, Germany Schauenburg, Hessen, Germany Bocholt, Nordrhein-Westfalen, Germany Essen, Nordrhein-Westfalen, Germany Isselburg, Nordrhein-Westfalen, Germany Köln, Nordrhein-Westfalen, Germany Roetgen, Nordrhein-Westfalen, Germany Troisdorf, Nordrhein-Westfalen, Germany Wesseling, Nordrhein-Westfalen, Germany Roedersheim-Gronau, Rheinland-Pfalz, Germany Dresden, Sachsen, Germany Freital, Sachsen, Germany Machem, Sachsen, Germany Markkleeberg, Sachsen, Germany Wermsdorf, Sachsen, Germany Bad Segeberg, Schleswig-Holstein, Germany Berlin, Germany Collapse << |
| NCT01227603 | Hypertension, Essential | Phase 1 | Completed | - | Germany ... more >> Köln, Nordrhein-Westfalen, Germany, 51063 Collapse << |
| NCT00400582 | Heart Failure | Phase 4 | Completed | - | Canada, Quebec ... more >> Montreal Heart Institute Montreal, Quebec, Canada, H1T 1C8 Collapse << |
| NCT02811731 | Hypertension | Phase 1 | Completed | - | - |
| NCT02988362 | Hypertension | Phase 1 | Unknown | March 2017 | - |
| NCT01629225 | Essential Hypertension | Phase 4 | Unknown | July 2015 | China ... more >> Department of Cardiology, Daping Hospital, The Third Military Medical University Recruiting Chongqing, China, 400042 Contact: Yu Changqing, MD changqingyu-2@163.com Collapse << |
| NCT02801526 | Hypertension | Phase 1 | Completed | - | - |
| NCT00843154 | Heart Failure | Phase 3 | Terminated(Insufficient enroll... more >>ment) Collapse << | - | - |
| NCT02944734 | Essential Hypertension | Phase 2 | Completed | - | Korea, Republic of ... more >> Catholic University of Korea Bucheon St. Mary's Hospital Wonmi-gu, Bucheon, Korea, Republic of Inje University Busan Paik Hospital Busanjin-gu, Busan, Korea, Republic of Pusan National University Hospital Seo-gu, Busan, Korea, Republic of Keimyung University Dongsan Medical Center Joong-gu, Daegu, Korea, Republic of Kyungpook National University Hospital Joong-gu, Daegu, Korea, Republic of Daegu Catholic University Medical Center Nam- gu, Daegu, Korea, Republic of Dongguk University Ilsan Hospital Ilsandong-gu, Goyang-si, Gyeoggi-do, Korea, Republic of Chonnam National University Hospital Dong-Gu, Gwangju, Korea, Republic of Catholic University of Korea Uijeongbu St. Mary's hospital Uijeongbu-si, Gyeoggi-do, Korea, Republic of Gachon University Gil Hospital Namdong-gu, Incheon, Korea, Republic of St. Carollo General Hospital Suncheon-si, Jeollanam-do, Korea, Republic of Wonju Severance Christian Hospital Wonju, Kangwon-Do, Korea, Republic of Catholic University of Korea St. Paul's Hospital Dongdaemun-gu, Seoul, Korea, Republic of KyungHee University Medical Center Dongdaemun-gu, Seoul, Korea, Republic of Hallym University Kangdong Sacred Heart Hospital Gangdong-gu, Seoul, Korea, Republic of Kyung Hee University Hospital at Gangdong Gangdong-Gu, Seoul, Korea, Republic of VHS( Veterans Medical Service) Medical Center Gangdong-gu, Seoul, Korea, Republic of Konkuk University Medical Center Gwangjin-gu, Seoul, Korea, Republic of Seoul National University Hospital Jongro-gu, Seoul, Korea, Republic of Catholic University of Korea Seoul St. Mary's Hospital Seocho-Gu, Seoul, Korea, Republic of Korea University Anam Hospital Seongbuk-Gu, Seoul, Korea, Republic of Catholic University of Korea Yeouido St. Mary's Hospital Yeongdeungpo-gu, Seoul, Korea, Republic of Ulsan University Hospital Dong-gu, Ulsan, Korea, Republic of Collapse << |
| NCT00775840 | Heart Failure | Phase 3 | Completed | - | Germany ... more >> Bad Friedrichshall, Baden-Württemberg, Germany Heidelberg, Baden-Württemberg, Germany Ludwigsburg, Baden-Württemberg, Germany Bad Homburg, Hessen, Germany Bad Nauheim, Hessen, Germany Darmstadt, Hessen, Germany Frankfurt, Hessen, Germany Giessen, Hessen, Germany Kassel, Hessen, Germany Limburg, Hessen, Germany Melsungen, Hessen, Germany Mühlheim, Hessen, Germany Wiesbaden, Hessen, Germany Nienburg, Niedersachsen, Germany Northeim, Niedersachsen, Germany Weyhe, Niedersachsen, Germany Essen, Nordrhein-Westfalen, Germany Gelsenkirchen, Nordrhein-Westfalen, Germany Gladbeck, Nordrhein-Westfalen, Germany Langenfeld, Nordrhein-Westfalen, Germany Paderborn, Nordrhein-Westfalen, Germany Siegen, Nordrhein-Westfalen, Germany Bad Kreuznach, Rheinland-Pfalz, Germany Neukirchen, Saarland, Germany Coswig, Sachsen-Anhalt, Germany Dresden, Sachsen, Germany Hartmannsdorf, Sachsen, Germany Leipzig, Sachsen, Germany Leisnig, Sachsen, Germany Machem, Sachsen, Germany Markkleeberg, Sachsen, Germany Riesa, Sachsen, Germany Wermsdorf, Sachsen, Germany Erfurt, Thüringen, Germany Jena, Thüringen, Germany Nordhausen, Thüringen, Germany Berlin, Germany Collapse << |
| NCT00620178 | - | - | Completed | - | Sweden ... more >> Research Site Uppsala, Sweden Collapse << |
| NCT00634400 | Congestive Heart Failure | Phase 3 | Completed | - | - |
| NCT00120003 | Stroke | Phase 3 | Completed | - | Norway ... more >> Ullevaal University Hospital Oslo, Norway, NO-0407 Collapse << |
| NCT01611077 | Hypertension | Phase 4 | Completed | - | Germany ... more >> Praxis Dr. Reimer Anderbeck, Germany, 38836 Praxis Dr. Heinz Bergisch-Gladbach, Germany, 51429 Praxis Dr. Zemmrich Berlin, Germany, 12043 St.-Josefs-Hospital Cloppenburg, Germany, 49661 Praxis Dr. Pohl Dresden, Germany, 01129 Praxis Dr. Koßler-Wiesweg Essen, Germany, 45138 Praxis Dr. Rövenich Frankfurt, Germany, 65929 Praxis Dr. Strzata Kapellendorf, Germany, 99510 Praxis Dr. Paschmionka Leipzig, Germany, 04316 Praxis Dr. Pitule Ludwigshafen, Germany, 67061 Praxis Dr. Loddo Rastede, Germany, 26180 Collapse << |
| NCT00383929 | Hypertension | Phase 3 | Completed | - | - |
| NCT01827202 | Hypertension ... more >>Chronic Kidney Disease Proteinuria Collapse << | Phase 4 | Completed | - | Austria ... more >> Medical University of Vienna, Department of Internal Medicine III, Division of Nephrology and Dialysis Vienna, Austria, 1090 Collapse << |
| NCT00348686 | - | - | Completed | - | - |
| NCT00348686 | Hypertension ... more >>Left Ventricular Hypertrophy Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Research Site BuSan, Korea, Republic of Research Site CheonAn, Korea, Republic of Research Site CheongJu, Korea, Republic of Research Site Chunbuk, Korea, Republic of Research Site DaeGu, Korea, Republic of Research Site DaeJeon, Korea, Republic of Research Site Gyungsangnamdo, Korea, Republic of Research Site JeonJu, Korea, Republic of Research Site KwangJu, Korea, Republic of Research Site Pusan, Korea, Republic of Research Site Ulsan, Korea, Republic of Collapse << |
| NCT02059616 | Essential Hypertension | Phase 2 | Unknown | December 2015 | Korea, Republic of ... more >> Seoul National University Bundang Hospital Recruiting Bundang, Korea, Republic of Dong-A University Hospital Recruiting Busan, Korea, Republic of Yeungnam University Medical Center Recruiting Daegu, Korea, Republic of Konyang University Hospital Recruiting Daejeon, Korea, Republic of Chonnam National University Hospital Recruiting Gwangju, Korea, Republic of Inje University Ilsan Paik Hospital Recruiting Ilsan, Korea, Republic of Inha University Hospital Recruiting Incheon, Korea, Republic of Hallym University Sacred Heart hospital Recruiting Kyungki-do, Korea, Republic of Inje University Haeundae Baik Hospital Recruiting Pusan, Korea, Republic of Pusan National University Hospital Recruiting Pusan, Korea, Republic of Asan Medical Center Recruiting Seoul, Korea, Republic of Ewha Womans University Mokdong Hospital Recruiting Seoul, Korea, Republic of Korea University Guro Hospital Recruiting Seoul, Korea, Republic of Seoul Medical Center Recruiting Seoul, Korea, Republic of Seoul St. Mary's hospital Recruiting Seoul, Korea, Republic of Severance Hospital Recruiting Seoul, Korea, Republic of Soonchunhyang University Hospital Recruiting Seoul, Korea, Republic of Yonsei University Gangnam Severance Hospital Recruiting Seoul, Korea, Republic of Ajou University Hospital Recruiting Suwon, Korea, Republic of Principal Investigator: Seung-Jea Tahk Wonju Severance Christian Hospital Recruiting Wonju, Korea, Republic of Collapse << |
| NCT01806311 | Hypertension | Phase 1 | Completed | - | Korea, Republic of ... more >> Chungnam national university hospital,clinical trial center Daejeon, Chungcheongbul-do, Korea, Republic of, 301-721 Collapse << |
| NCT02173912 | Healthy Volunteers | Phase 1 | Unknown | August 2014 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Korea, Republic of Contact: Chaeyeong Lee Principal Investigator: Jae-Wook Ko, MD Collapse << |
| NCT02969265 | Hypertension | Phase 3 | Withdrawn(Business reasons unr... more >>elated to product safety) Collapse << | July 26, 2018 | - |
| NCT01984164 | Hypertension ... more >>Mild Cognitive Impairment Collapse << | Phase 3 | Active, not recruiting | December 15, 2018 | United States, Georgia ... more >> Emory Univeristy Atlanta, Georgia, United States, 30329 Collapse << |
| NCT02047019 | Hypertension | Phase 3 | Withdrawn(GPDC decided to term... more >>inate the study) Collapse << | December 8, 2019 | Italy ... more >> Fondazione Università G.D'Annunzio Chieti, Abruzzo, Italy, 66100 A.O.U. di Bologna Policlinico S.Orsola Malpighi Bologna, Emilia-Romagna, Italy, 40138 AAS 3 Friuli Alto Medio Collin Udine, Friuli-Venezia Giulia, Italy, 33038 Fondazione Salvatore Maugeri Pavia, Lombardia, Italy, 27100 IRCCS Ist Neurologico Mediterraneo Isernia, Molise, Italy, 86077 A.O.U. di Sassari Sassari, Sardegna, Italy, 07100 A.O.U. Pisana Pisa, Toscana, Italy, 56126 AULSS 07 Pieve Soligo Treviso, Veneto, Italy, 31029 Collapse << |
| NCT03460327 | - | - | Recruiting | October 2026 | Norway ... more >> St. Olavs University Hospital Recruiting Trondheim, Norway Contact: Magnus Strømmen, MSc Collapse << |
| NCT00984529 | - | - | Completed | - | Croatia ... more >> Research Site Biograd, Croatia Research Site Bjelovar, Croatia Reserach Site Cakovec, Croatia Research Site Karlovac, Croatia Reserach Site Krapinske Toplice, Croatia Research Site Novi Marof, Croatia Research Site Opatija, Croatia Research Site Osijek, Croatia Research Site Pula, Croatia Research Site Rijeka, Croatia Reserach Site Sl. Brod, Croatia Research Site Split, Croatia Research Site Stubicke Toplice, Croatia Reserach Site Zabok, Croatia Research Site Zagreb, Croatia Collapse << |
| NCT00244621 | - | - | Completed | - | - |
| NCT00699452 | Aortic Valve Stenosis | Phase 3 | Unknown | December 2014 | Finland ... more >> Division of Cardiology, Helsinki University Central Hospital Recruiting Helsinki, Finland, 00029 Contact: Markku Kupari, MD, PhD 358-9-4717-2441 markku.kupari@hus.fi Contact: Satu Helske, MD, PhD 358-9-681-411 satu.helske@wri.fi Principal Investigator: Markku Kupari, MD, PhD Collapse << |
| NCT00434967 | Hypertension | Phase 3 | Completed | - | Belgium ... more >> Research Site Dour, Belgium Research Site Gozée, Belgium Research Site Hasselt, Belgium Research Site Linkebeek, Belgium Research Site Marchovelette, Belgium Research Site Ronquières, Belgium Research Site Saint-Médard, Belgium Research Site Steenokkerzel, Belgium Latvia Research Site Daugavpils, Latvia Research Site Ogre, Latvia Research Site Riga, Latvia Malta Research Site Gozo, Malta Research Site Gwardiamangia, Malta Romania Research Site Arad, Romania Research Site Bucuresti, Romania Research Site Iasi, Romania Research Site Pitesti, Romania Research Site Ploiesti, Romania Research Site Targoviste, Romania Research Site Timisoara, Romania Russian Federation Research Site Moscow, Russian Federation Research Site St. Petersburg, Russian Federation Slovakia Research Site Bratislava, Slovakia Research Site Levice, Slovakia Research Site Lucenec, Slovakia Research Site Presov, Slovakia Research Site Sahy, Slovakia Collapse << |
| NCT00434967 | - | - | Completed | - | - |
| NCT00244621 | Hypertension | Phase 3 | Completed | - | - |
| NCT01938664 | Cocaine Dependence | Phase 2 | Completed | - | United States, Texas ... more >> Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 Collapse << |
| NCT02068495 | - | - | Completed | - | - |
| NCT00690612 | Hypertension | Phase 3 | Completed | - | Belgium ... more >> Research Site Edegem, Belgium Research Site Gent, Belgium France Research Site Strasbourg Cedex, France Germany Research Site Erlangen, Germany Research Site Heidelberg, Germany Research Site Marburg, Germany Research Site Rostock, Germany Italy Research Site Genova, GE, Italy Research Site Padova, PD, Italy Poland Research Site Gda�sk, Poland Research Site Krakow, Poland Ukraine Research Site Crimea, Ukraine Research Site Kyiv, Ukraine Collapse << |
| NCT01350609 | Hypertension, Essential | Phase 1 | Completed | - | Germany ... more >> Berlin, Germany, 13353 Collapse << |
| NCT02068495 | - | - | Completed | - | - |
| NCT00679640 | - | - | Completed | - | - |
| NCT00139386 | Hypertension ... more >>Coronary Artery Disease Collapse << | Phase 4 | Completed | - | Japan ... more >> Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University Kumamoto, Japan, 860-8556 Collapse << |
| NCT02094924 | Hypertension | Phase 1 | Completed | - | India ... more >> GSK Investigational Site Hyderabad, India, 500 013 Collapse << |
| NCT00634309 | Congestive Heart Failure | Phase 3 | Completed | - | - |
| NCT00690612 | - | - | Completed | - | - |
| NCT03136666 | Clinical Pharmacology | Phase 1 | Completed | - | Germany ... more >> Wuppertal, Nordrhein-Westfalen, Germany, 42096 Collapse << |
| NCT00573430 | Non-diabetic Nephropathy With ... more >>Hypertension Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Research Site Seoul, Korea, Republic of Collapse << |
| NCT00634712 | Congestive Heart Failure | Phase 3 | Completed | - | - |
| NCT00844324 | Hypertension | Phase 1 | Completed | - | United Kingdom ... more >> Research Site Harrow, United Kingdom Collapse << |
| NCT01976572 | Hyperphosphatemia ... more >> Chronic Kidney Disease Collapse << | Phase 1 | Completed | - | United Kingdom ... more >> Covance Clinical Research Unit Ltd. Leeds, Springfield House Hyde Street, United Kingdom Collapse << |
| NCT00573430 | - | - | Completed | - | - |
| NCT00990639 | Alcoholic Liver Disease | Phase 1 Phase 2 | Completed | - | Korea, Republic of ... more >> Yonsei University Wonju College of Medicine Wonju Christian Hospital Wonju, Kangwon-do, Korea, Republic of, 220-701 Collapse << |
| NCT01976572 | - | - | Completed | - | - |
| NCT00252720 | Type 1 Diabetes | Phase 3 | Completed | - | - |
| NCT00252720 | - | - | Completed | - | - |
| NCT00227318 | Hypertension | Phase 3 | Completed | - | - |
| NCT01788358 | Hypertension | Phase 3 | Completed | - | - |
| NCT00252694 | - | - | Completed | - | - |
| NCT00252733 | Type 1 Diabetes | Phase 3 | Completed | - | Australia ... more >> Research Site Herston, Australia Research Site Perth, Australia Denmark Research Site Odense, Denmark Collapse << |
| NCT02016183 | - | - | Completed | - | Japan ... more >> Tokyo, Japan Collapse << |
| NCT00252694 | Type 2 Diabetes | Phase 3 | Completed | - | - |
| NCT01788358 | - | - | Completed | - | - |
| NCT01012479 | Hypertension | Phase 4 | Completed | - | Germany ... more >> Berlin, Germany Blankenhain, Germany Dortmund, Germany Hamburg, Germany Köthen, Germany Löhne, Germany Nürnberg, Germany Remscheid, Germany Rodgau, Germany Stockach, Germany Wardenburg, Germany Weinheim, Germany Ukraine Ivano-Frankivsk, Ukraine Kharkiv, Ukraine Kiev, Ukraine Lviv, Ukraine Collapse << |
| NCT02016183 | - | - | Completed | - | - |
| NCT00252733 | - | - | Completed | - | - |
| NCT00621153 | - | - | Completed | - | - |
| NCT00621153 | Stage II Hypertension | Phase 4 | Completed | - | Korea, Republic of ... more >> Research Site Seoul, Korea, Republic of Collapse << |
| NCT00242346 | Proteinuria | Phase 3 | Completed | - | Canada, Alberta ... more >> Research Site Calgary, Alberta, Canada Research Site Edmonton, Alberta, Canada Canada, British Columbia Research Site Kelowna, British Columbia, Canada Research Site Vancouver, British Columbia, Canada Canada, Manitoba Research Site Winnipeg, Manitoba, Canada Canada, Newfoundland and Labrador Research Site St. John, Newfoundland and Labrador, Canada Canada, Nova Scotia Research Site Halifax, Nova Scotia, Canada Canada, Ontario Research Site Courtice, Ontario, Canada Research Site Kitchener, Ontario, Canada Research Site London, Ontario, Canada Research Site Mississauga, Ontario, Canada Research Site Oakville, Ontario, Canada Research Site Oshawa, Ontario, Canada Research Site Richmond Hill, Ontario, Canada Research Site Scarborough, Ontario, Canada Research Site Sudbury, Ontario, Canada Research Site Thunder Bay, Ontario, Canada Research Site Timmins, Ontario, Canada Research Site Toronto, Ontario, Canada Research Site Weston, Ontario, Canada Canada, Quebec Research Site Greenfield Park, Quebec, Canada Research Site Laval, Quebec, Canada Research Site Montreal, Quebec, Canada Research Site Quebec City, Quebec, Canada Research Site Ste-Foy, Quebec, Canada Canada, Saskatchewan Research Site Saskatoon, Saskatchewan, Canada Collapse << |
| NCT02368665 | Essential Hypertension | Phase 3 | Unknown | June 2016 | Korea, Republic of ... more >> Hallym University Sungsim Hospital Recruiting Anyang-si, Korea, Republic of Inje University Busan Baik Hospital Recruiting Busan, Korea, Republic of Inje University Haeundae Baik Hospital Recruiting Busan, Korea, Republic of Yeungnam University Medical Center Recruiting Daegu, Korea, Republic of Chonnam National University Hospital Recruiting Gwangju, Korea, Republic of Inje University Ilsan Baik Hospital Recruiting Ilsan, Korea, Republic of Inha University Hospital Recruiting Incheon, Korea, Republic of Seoul National University Bundang Hospital Recruiting Seongnam-si, Korea, Republic of Asan Medical Center Recruiting Seoul, Korea, Republic of Ewha Womans University Mokdong Hospital Recruiting Seoul, Korea, Republic of Gangbuk Samsung Hospital Recruiting Seoul, Korea, Republic of Korea University Anam Hospital Recruiting Seoul, Korea, Republic of Korea University Guro Hospital Recruiting Seoul, Korea, Republic of Seoul Medical Center Recruiting Seoul, Korea, Republic of Seoul St. Mary's Hospital Catholic University Recruiting Seoul, Korea, Republic of Soonchunhyang University Hospital Recruiting Seoul, Korea, Republic of Yonsei University Severance Hospital Recruiting Seoul, Korea, Republic of Ajou University Hospital Recruiting Suwon, Korea, Republic of Principal Investigator: Seungjae Tahk Wonju Severance Christian Hospital Recruiting Wonju, Korea, Republic of Collapse << |
| NCT02646982 | Mild Cognitive Impairment | Phase 2 | Recruiting | September 2021 | United States, Georgia ... more >> Emory University Recruiting Atlanta, Georgia, United States, 30322 Contact: Ihab Hajjar, MD 404-712-7250 ihajjar@emory.edu Principal Investigator: Ihab Hajjar, MD Wesley Woods Center Recruiting Atlanta, Georgia, United States, 30329 Contact: Ihab Hajjar, MD 404-712-7250 ihajjar@emory.edu Collapse << |
| NCT01926652 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Chungnam national university hospital, clinical trial center Daejeon, Chungcheongbul-do, Korea, Republic of, 301-721 Collapse << |
| NCT02254447 | Cardiovascular Disease | Phase 1 | Completed | - | India ... more >> GSK Investigational Site Hyderabad, India, 500 013 Collapse << |
| NCT02368652 | Essential Hypertension | Phase 3 | Unknown | June 2016 | Korea, Republic of ... more >> Hallym University Sungsim Hospital Recruiting Anyang-si, Korea, Republic of Inje University Busan Baik Hospital Recruiting Busan, Korea, Republic of Inje University Haeundae Baik Hospital Recruiting Busan, Korea, Republic of Yeungnam University Medical Center Recruiting Daegu, Korea, Republic of Chonnam National University Hospital Recruiting Gwangju, Korea, Republic of Inje University Ilsan Baik Hospital Recruiting Ilsan, Korea, Republic of Inha University Hospital Recruiting Incheon, Korea, Republic of Seoul National University Bundang Hospital Recruiting Seongnam-si, Korea, Republic of Asan Medical Center Recruiting Seoul, Korea, Republic of Ewha Womans University Mokdong Hospital Recruiting Seoul, Korea, Republic of Gangbuk Samsung Hospital Recruiting Seoul, Korea, Republic of Korea University Anam Hospital Recruiting Seoul, Korea, Republic of Korea University Guro Hospital Recruiting Seoul, Korea, Republic of Seoul Medical Center Recruiting Seoul, Korea, Republic of Seoul St. Mary's Hospital Catholic University Recruiting Seoul, Korea, Republic of Soonchunhyang University Hospital Recruiting Seoul, Korea, Republic of Yonsei University Severance Hospital Recruiting Seoul, Korea, Republic of Ajou University Hospital Recruiting Suwon, Korea, Republic of Principal Investigator: Seungjae Tahk Wonju Severance Christian Hospital Recruiting Wonju, Korea, Republic of Collapse << |
| NCT02064621 | Hypertension | Phase 1 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Songpa-gu, Korea, Republic of Collapse << |
| NCT02006602 | Hypertension | Phase 1 | Completed | - | India ... more >> GSK Investigational Site Hyderabad, India, 500 013 Collapse << |
| NCT01845272 | Healthy | Phase 1 | Unknown | August 2013 | - |
| NCT02166697 | - | - | Completed | - | - |
| NCT02166697 | - | - | Completed | - | - |
| NCT02211638 | - | - | Completed | - | - |
| NCT02211638 | - | - | Completed | - | Japan ... more >> Osaka, Japan Collapse << |
| NCT02006589 | Hypertension | Phase 1 | Completed | - | India ... more >> GSK Investigational Site Hyderabad, India, 500 013 Collapse << |
| 靶点 | Description | IC50 |
|---|---|---|
| Angiotensin Receptor | IC50:0.26nM |
