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CAS No.: 71720-56-4

非诺洛芬钙 Catalog No. CSN16015

Synonyms: Fenoprofen calcium salt dihydrate;Fenoprofen (calcium salt hydrate);Fenoprofen Calcium Dihydrate

Fenoprofen calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.

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技术信息

生物活性

描述Fenoprofen Calcium Dihydrate (FCD) is a nonsteroidal, anti-inflammatory antiarthritic agent. FCD is slightly water soluble. It is indicated for mild pain relief, where the suggested dosage is 200 mg orally every 4 to 6 h. Fenoprofen has a serum half-life of about 150 to 180 minutes and is at least 99% bound to plasma proteins. It is extensively metabolised after oral administration, the main metabolites being fenoprofen glucuronide and 4-hydroxy-fenoprofen glucuronide^[3]. Both fenoprofen, 200 mg, and fenoprofen, 400 mg, offered significant (P<0.01) pain relief when compared to placebo and aspirin. Fenoprofen, 200 mg, appears to be as effective as fenoprofen, 400 mg^[4]. Fenoprofen calcium is effective for use in treating soft-tissue injuries since it is better tolerated than aspirin when given in equally effective doses^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.7901 mL
- 8.9504 mL
- 17.9009 mL
- 5 mM
- 0.3580 mL
- 1.7901 mL
- 3.5802 mL
- 10 mM
- 0.1790 mL
- 0.8950 mL
- 1.7901 mL

技术信息

CAS号

71720-56-4

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C30H30CaO8

运输

蓝冰

分子量

558.63

别名

Fenoprofen calcium salt dihydrate;Fenoprofen (calcium salt hydrate);Fenoprofen Calcium Dihydrate

溶解度

DMSO	105.0 mg/mL (188.0 mM)
Water	insoluble

动物实验配方

30% propylene glycol+5% Tween 80+65% water

30 mg/mL

suspension

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