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CAS No.: 21802-37-9

Caerulomycin A Catalog No. CSN20423

Synonyms: Cerulomycin;Caerulomycin;Carulomycin A

Caerulomycin A is a rare and unusual antibiotic containing a core 2, 2'-bispyridyl with an oxime substituent, isolated and purified from a strain of Streptomyces caeruleus.

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生物活性

描述Caerulomycin A is a rare and unusual antibiotic containing a core 2, 2'-bispyridyl with an oxime substituent, isolated and purified from a strain of Streptomyces caeruleus. Caerulomycin is active against fungi and some protozoans, and is weakly active against bacteria. Caerulomycin A suppresses the differentiation of naive T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis.
参考文献

[1] Kujur W, Gurram RK, et al. Caerulomycin A inhibits Th2 cell activity: a possible role in the management of asthma. Sci Rep. 2015 Oct 20;5:15396.
[2] Gurram RK, Kujur W, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.3623 mL
- 21.8117 mL
- 43.6234 mL
- 5 mM
- 0.8725 mL
- 4.3623 mL
- 8.7247 mL
- 10 mM
- 0.4362 mL
- 2.1812 mL
- 4.3623 mL

技术信息

CAS号	21802-37-9	储存条件	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C12H11N3O2	运输	蓝冰
分子量	229.23	别名	Cerulomycin;Caerulomycin;Carulomycin A;AC1N-THG8;AC1N THG8 NSC-114341;HE-185727

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