CAS No.: 1192810-88-0
Bms-902483 Catalog No. CSN19722
BMS-902483 is a potent α7 nicotinic acetylcholine receptor partial agonist, which improved cognition in preclinical rodent models.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Cook J, Zusi FC, et al. Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2] octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship. J Med Chem. 2016 Dec 22;59(24):11171-11181.
- [2] Pieschl RL, Miller R, et al. Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents. Eur J Pharmacol. 2017 Apr 22;807:1-11.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1192810-88-0 | 储存条件 |
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| 分子式 | C18H20N4O | 运输 | 蓝冰 | |
| 分子量 | 308.38 | 别名 |
