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CAS No.: 195987-41-8
Synonyms: 7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine
BMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00004877 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
NCT00022529 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111-2497 Collapse << |
NCT00005973 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
实验方案
技术信息
CAS号 | 195987-41-8 | 储存条件 |
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分子式 | C25H23N5O2S2 | 运输 | 蓝冰 | |
分子量 | 489.61 | 别名 | 7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00004877 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10021 Collapse << |
NCT00022529 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111-2497 Collapse << |
NCT00005973 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT00006018 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Ohio ... more >> Ireland Cancer Center at University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106-5065 Arthur G. James Cancer Hospital - Ohio State University Columbus, Ohio, United States, 43210-1240 Collapse << |
NCT00006242 | Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Massachusetts ... more >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 Collapse << |
NCT00006213 | Adult Acute Promyelocytic Leuk... more >>emia (M3) Blastic Phase Chronic Myelogenous Leukemia Childhood Myelodysplastic Syndromes Previously Treated Myelodysplastic Syndromes Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Refractory Anemia With Excess Blasts Refractory Anemia With Excess Blasts in Transformation Relapsing Chronic Myelogenous Leukemia Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
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