|1-(二环[2.2.1]庚-5-烯-2-基)-1-苯基-3-(哌啶-1-基)丙-1-醇盐酸盐|CsnPharm

CAS No.: 1235-82-1

Biperiden HCl/盐酸比哌立登 Catalog No. CSN10454

Synonyms: KL 373 hydrochloride;NSC 170950;NSC-84989

Biperiden HCl is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.

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实验方案

技术信息

生物活性

描述Biperiden hydrochloride is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT02078336	Dental Care for Disabled	Phase 4	Unknown	August 2014	Belgium ... more >> Katholieke Universiteit Leuven Recruiting Leuven, Belgium, 3000 Contact: Dominique Declerck dominique.declerck@med.kuleuven.be Contact: Ine Opsomer ine.opsomer@uzleuven.be Collapse <<
NCT03730857	Schizophrenia	Phase 1	Completed	-	-
NCT02374567	Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse <<	Phase 3	Terminated	-	Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse <<

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参考文献

[1] Kornhuber J, Muehlbacher M, et al. Identification of novel functional inhibitors of acid sphingomyelinase. PLoS One. 2011;6(8):e23852.
[2] Pehl C, Wendl B, et al. Effects of two anticholinergic drugs, trospium chloride and biperiden, on motility and evoked potentials of the oesophagus. Aliment Pharmacol Ther. 1998 Oct;12(10):979-84.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.8742 mL
- 14.3710 mL
- 28.7421 mL
- 5 mM
- 0.5748 mL
- 2.8742 mL
- 5.7484 mL
- 10 mM
- 0.2874 mL
- 1.4371 mL
- 2.8742 mL

技术信息

CAS号	1235-82-1	储存条件	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C21H30ClNO	运输	蓝冰
分子量	347.92	别名	KL 373 hydrochloride;NSC 170950;NSC-84989;Biperiden (hydrochloride);Akineton;Akinophyl;Akineton hydrochloride;Biperiden Hydrochloride;盐酸比哌立登

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02078336	Dental Care for Disabled	Phase 4	Unknown	August 2014	Belgium ... more >> Katholieke Universiteit Leuven Recruiting Leuven, Belgium, 3000 Contact: Dominique Declerck dominique.declerck@med.kuleuven.be Contact: Ine Opsomer ine.opsomer@uzleuven.be Collapse <<
NCT03730857	Schizophrenia	Phase 1	Completed	-	-
NCT02374567	Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse <<	Phase 3	Terminated	-	Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse <<
NCT00495092	Cocaine Related Disorders	Phase 2 Phase 3	Completed	-	Spain ... more >> Hospital Universitari Vall d'Hebron Barcelona, Catalonia, Spain, 08035 Collapse <<
NCT01251393	Cocaine Dependence ... more >> Crack Cocaine Dependence Collapse <<	Phase 3	Completed	-	Brazil ... more >> UDED - Drug Dependence Unit São Paulo, Brazil, 04024-003 Collapse <<
NCT00495183	Cocaine Dependence	Phase 4	Unknown	July 2010	Spain ... more >> Hospital Universitari Vall d'Hebron Recruiting Barcelona, Catalonia, Spain, 08035 Contact: Miquel Casas, Prof 0034 93 489 42 94 mcasas@vhebron.net Contact: Xavier Castells, MD xcc@icf.uab.cat Sub-Investigator: Carlos Roncero, MD Sub-Investigator: Castells Xavier, MD Sub-Investigator: Gonzalvo Begoña, MD Collapse <<
NCT01048138	Traumatic Brain Injury	Phase 3	Recruiting	January 31, 2020	Brazil ... more >> Federal University of São Paulo Recruiting Sao Paulo, Brazil Contact: Luiz EM Mello 55-11-55792033 lemello@unifesp.br Principal Investigator: Luiz EM Mello Collapse <<
NCT02374567	Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse <<	Phase 3	Terminated	-	Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse <<
NCT03730857	Schizophrenia	Phase 1	Completed	-	-
NCT02078336	Dental Care for Disabled	Phase 4	Unknown	August 2014	Belgium ... more >> Katholieke Universiteit Leuven Recruiting Leuven, Belgium, 3000 Contact: Dominique Declerck dominique.declerck@med.kuleuven.be Contact: Ine Opsomer ine.opsomer@uzleuven.be Collapse <<
NCT01251393	Cocaine Dependence ... more >> Crack Cocaine Dependence Collapse <<	Phase 3	Completed	-	Brazil ... more >> UDED - Drug Dependence Unit São Paulo, Brazil, 04024-003 Collapse <<
NCT00495092	Cocaine Related Disorders	Phase 2 Phase 3	Completed	-	Spain ... more >> Hospital Universitari Vall d'Hebron Barcelona, Catalonia, Spain, 08035 Collapse <<
NCT01048138	Traumatic Brain Injury	Phase 3	Recruiting	January 31, 2020	Brazil ... more >> Federal University of São Paulo Recruiting Sao Paulo, Brazil Contact: Luiz EM Mello 55-11-55792033 lemello@unifesp.br Principal Investigator: Luiz EM Mello Collapse <<
NCT00495183	Cocaine Dependence	Phase 4	Unknown	July 2010	Spain ... more >> Hospital Universitari Vall d'Hebron Recruiting Barcelona, Catalonia, Spain, 08035 Contact: Miquel Casas, Prof 0034 93 489 42 94 mcasas@vhebron.net Contact: Xavier Castells, MD xcc@icf.uab.cat Sub-Investigator: Carlos Roncero, MD Sub-Investigator: Castells Xavier, MD Sub-Investigator: Gonzalvo Begoña, MD Collapse <<

Biperiden HCl/盐酸比哌立登 Catalog No. CSN10454

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