CAS No.: 732983-37-8
BAY 61-3606 Catalog No. CSN18411
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Lau KS, Zhang T, et al. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One. 2012;7(7):e41343.
- [2] Yamamoto N, Takeshita K, et al. The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c] pyrimidin-5-ylamino] nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents. J Pharmacol Exp Ther. 2003 Sep;306(3):1174-81.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 732983-37-8 | 储存条件 |
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| 分子式 | C20H18N6O3 | 运输 | 蓝冰 | |
| 分子量 | 390.40 | 别名 |
