生物活性

• 描述Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic. It is an N-acyloxymethyl prodrug of aripiprazole that is administered via intramuscular injection once every four to six weeks for the treatment of schizophrenia.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT01469039	Schizophrenia	Phase 3	Completed	-	-
  NCT03345979	Schizophrenia	Phase 3	Active, not recruiting	August 2019	United States, Arkansas ... more >> Alkermes Investigational Site Little Rock, Arkansas, United States, 72211 Alkermes Investigational Site Rogers, Arkansas, United States, 72758 United States, California Alkermes Investigational Site Cerritos, California, United States, 90703 Alkermes Investigational Site Culver City, California, United States, 90230 Alkermes Investigational Site Garden Grove, California, United States, 92845 Alkermes Investigational Site Lemon Grove, California, United States, 91945 United States, Florida Alkermes Investigational Site Hialeah, Florida, United States, 33012 United States, Illinois Alkermes Investigational Site Chicago, Illinois, United States, 60640 Alkermes Investigational Site Hoffman Estates, Illinois, United States, 60169 United States, Mississippi Alkermes Investigational Site Flowood, Mississippi, United States, 39232 United States, Missouri Alkermes Investigational Site Saint Louis, Missouri, United States, 63141 United States, Nevada Alkermes Investigational Site Las Vegas, Nevada, United States, 89102 United States, New Jersey Alkermes Investigational Site Berlin, New Jersey, United States, 08009 United States, Texas Alkermes Investigational Site Austin, Texas, United States, 78754 Alkermes Investigational Site Garland, Texas, United States, 75042 Alkermes Investigational Site Richardson, Texas, United States, 75080 Collapse <<
  NCT01469039	-	-	Completed	-	-

• 更多
• 参考文献

• [1] Nasrallah HA, Newcomer JW, et al. Effect of Aripiprazole Lauroxil on Metabolic and Endocrine Profiles and Related Safety Considerations Among Patients With Acute Schizophrenia. J Clin Psychiatry. 2016 Nov;77(11):1519-1525.

  [2] Rohde M, M Rk N, et al. Biological conversion of aripiprazole lauroxil - An N-acyloxymethyl aripiprazole prodrug. Results Pharma Sci. 2014 May 2;4:19-25.