CAS No.: 118458-54-1
Arcyriaflavin A Catalog No. CSN20471
Arcyriaflavin A is a potent inhibitor of cdk4/cyclin D1 (IC50 = 59 nM) and CaM kinase II (IC50 = 25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are > 2 and > 100 μM respectively). It can also inhibit human cytomegalovirus (HCMV) replication in vitro (IC50 = 200 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Hirakawa T, Nasu K, et al. Arcyriaflavin a, a cyclin D1-cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis. Reprod Biol Endocrinol. 2017 Jul 18;15(1):53.
- [2] Slater MJ, Cockerill S, et al. Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication. Bioorg Med Chem. 1999 Jun;7(6):1067-74.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 118458-54-1 | 储存条件 |
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| 分子式 | C20H11N3O2 | 运输 | 蓝冰 | |
| 分子量 | 325.32 | 别名 |
