CAS No.: 145782-74-7
AR-C66096 tetrasodium/AR-C 66096四钠盐 Catalog No. CSN20192
AR-C 66096 tetrasodium is a potent and selective P2Y12 receptor antagonist which blocks ADP-induced inhibition of adenylyl cyclase in vitro (pKB =7.6) and inhibits ADP-induced aggregation of washed human platelets (pIC50 = 8.16).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Mitrugno A, Rigg RA, et al. Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y(12) signaling with MRS2395. Platelets. 2017 May 19:1-12.
- [2] Gunduz D, Tanislav C, Schluter KD, Schulz R, Hamm C, Aslam M. Effect of ticagrelor on endothelial calcium signalling and barrier function. Thromb Haemost. 2017 Jan 26;117(2):371-381.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 145782-74-7 | 储存条件 |
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| 分子式 | C14H18F2N5Na4O12P3S | 运输 | 蓝冰 | |
| 分子量 | 703.26 | 别名 |
