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CAS No.: 16611-84-0
Synonyms: Hydroginkgolic acid;Ginkgolic Acid C15:0;6-Pentadecylsalicylic Acid
Anacardic acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity,prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.
生物活性
实验方案
技术信息
CAS号 | 16611-84-0 | 储存条件 |
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分子式 | C22H36O3 | 运输 | 蓝冰 | |||||||||
分子量 | 348.52 | 别名 | Hydroginkgolic acid;Ginkgolic Acid C15:0;6-Pentadecylsalicylic Acid;漆树酸 | |||||||||
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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HCT116 cells | - | Cytotoxicity assay | 72 h | Cytotoxicity against human HCT116 cells after 72 hrs by luciferase reporter gene assay, IC50=0.38 μM | 23245311 |
Hi5 cells | - | Function assay | - | Non-competitive inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells | 23245311 |
Hi5 cells | - | Function assay | - | Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir to substrate addition measured after 90 mins by NADH coupled assay, IC50=0.024 μM | 23245311 |
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