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CAS No.: 137-88-2

Amprolium HCl/盐酸氨丙啉 Catalog No. CSN10304

Synonyms: Amprolium (hydrochloride);Amprol;Amprol 25

Amprolium HCl is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake.

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技术信息

生物活性

描述Amprolium hydrochloride is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake it prevents carbohydrate synthesis. Amprolium hydrochloride was not efficacious against clinical coccidiosis in both the experimental and field trials^[3]. Amprolium exposure induced weight loss with hyporexia, reduced the behavioral parameters (locomotion, exploratory activity, and motor coordination), and induced changes in the brain (lower cortical cell viability) and liver (steatosis) ^[4]. Moreover, both toltrazuril, amprolium and their concurrent use significantly reduced OPG (oocysts per gram) and effectively controlled coccidiosis related mortality, fully abolished the clinical signs, improved feed consumption, BW (body weight), weight gain and feed conversion rate. The oral administration of both drugs and their combined use ameliorated the adverse impacts of intestinal coccidiosis in rabbits as therapeutic, but the concurrent use of both drugs was more superior. ^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.1722 mL
- 15.8609 mL
- 31.7217 mL
- 5 mM
- 0.6344 mL
- 3.1722 mL
- 6.3443 mL
- 10 mM
- 0.3172 mL
- 1.5861 mL
- 3.1722 mL

技术信息

CAS号

137-88-2

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C14H20Cl2N4

运输

蓝冰

分子量

315.24

别名

Amprolium (hydrochloride);Amprol;Amprol 25;Thiacoccid;NSC-523454;Amprolium HCl;氨丙啉盐酸盐;盐酸氨丙林

溶解度

DMSO	2.0 mg/mL (6.3 mM)
Ethanol	Insoluble

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