CAS No.: 185991-07-5
AMD 3465 6HBr Catalog No. CSN16529
Synonyms: GENZ-644494 hexahydrobromide;AMD 3465 (hydrobromide);AMD3465 HBr
AMD 3465 hexahydrobromide is a potent, selective CXCR4 antagonist and exhibits 8-fold higher affinity than AMD 3100 and inhibits SDF-1α-ligand binding (Ki = 41.7 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Bodart V, Anastassov V, et al. Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4. Biochem Pharmacol. 2009 Oct 15;78(8):993-1000.
- [2] Rosenkilde MM, Gerlach LO, et al. Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor. J Biol Chem. 2007 Sep 14;282(37):27354-65. Epub 2007 Jun 28.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 185991-07-5 | 储存条件 |
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| 分子式 | C24H44Br6N6 | 运输 | 蓝冰 | |
| 分子量 | 896.07 | 别名 | GENZ-644494 hexahydrobromide;AMD 3465 (hydrobromide);AMD3465 HBr;AMD3465 hydrobromide;AMD-3465;GENZ-644494 |
