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CAS No.: 1818393-16-6
Synonyms: APG-115;AA-115
APG-115 is a compound with a very high affinity to MDM2 (Ki < 1 nM), potent cellular activity, and an excellent oral pharmacokinetic profile.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02935907 | Patients With Advanced Solid T... more >>umor or Lymphoma Collapse << | Phase 1 | Recruiting | October 2018 | United States, Michigan ... more >> START Midwest Recruiting Grand Rapids, Michigan, United States, 49503 Contact: Kathy Estkowski, BS, CCRP 616-954-5554 kathy.estkowski@startmidwest.com Contact: Yvette C Cole, RN, BSN, OCN 616-954-5554 yvette.cole@startmidwest.com Principal Investigator: Nehal Lakhani, M.D., Ph.D. United States, Texas The START Center for Cancer Care Recruiting San Antonio, Texas, United States, 78229 Contact: Isabel Jimenez, RN, MSN 210-593-5265 isabel.jimenez@start.stoh.com Collapse << |
NCT03611868 | Unresectable or Metastatic Mel... more >>anoma or Advanced Solid Tumors Collapse << | Phase 1 Phase 2 | Recruiting | May 15, 2021 | United States, Texas ... more >> Next Oncology Recruiting San Antonio, Texas, United States, 78240 Collapse << |
实验方案
技术信息
CAS号 | 1818393-16-6 | 储存条件 |
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分子式 | C34H38Cl2FN3O4 | 运输 | 蓝冰 | |
分子量 | 642.59 | 别名 | APG-115;AA-115 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02935907 | Patients With Advanced Solid T... more >>umor or Lymphoma Collapse << | Phase 1 | Recruiting | October 2018 | United States, Michigan ... more >> START Midwest Recruiting Grand Rapids, Michigan, United States, 49503 Contact: Kathy Estkowski, BS, CCRP 616-954-5554 kathy.estkowski@startmidwest.com Contact: Yvette C Cole, RN, BSN, OCN 616-954-5554 yvette.cole@startmidwest.com Principal Investigator: Nehal Lakhani, M.D., Ph.D. United States, Texas The START Center for Cancer Care Recruiting San Antonio, Texas, United States, 78229 Contact: Isabel Jimenez, RN, MSN 210-593-5265 isabel.jimenez@start.stoh.com Collapse << |
NCT03611868 | Unresectable or Metastatic Mel... more >>anoma or Advanced Solid Tumors Collapse << | Phase 1 Phase 2 | Recruiting | May 15, 2021 | United States, Texas ... more >> Next Oncology Recruiting San Antonio, Texas, United States, 78240 Collapse << |
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