CAS No.: 893422-47-4
Akt1/Akt2-IN-1 Catalog No. CSN18535
Synonyms: Akti_2008;Akti-2008;Akt-Inhibitor-17
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50 = 42 nM), with potent and balanced activity.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Li Y, Liang J, et al. Allosteric inhibitors of Akt1 and Akt2: discovery of [1,2,4] triazolo[3,4-f] [1,6] naphthyridines with potent and balanced activity. Bioorg Med Chem Lett. 2009 Feb 1;19(3):834-6.
- [2] Bilodeau MT, Balitza AE, et al. Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3178-82.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 893422-47-4 | 储存条件 |
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| 分子式 | C33H29N7O | 运输 | 蓝冰 | |
| 分子量 | 539.63 | 别名 | Akti_2008;Akti-2008;Akt-Inhibitor-17 |
