CAS No.: 1000279-69-5
A-867744 Catalog No. CSN17376
A-867744 is a positive allosteric modulator of α7 nAChRs (IC50 values are 0.98 and 1.12 μM for human and rat α7 receptor ACh-evoked currents respectively, in X.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Malysz J, Anderson DJ, et al. In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107. J Pharmacol Exp Ther. 2010 Sep 1;334(3):863-74.
- [2] Faghih R, Gopalakrishnan SM, et al. Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor. J Med Chem. 2009 May 28;52(10):3377-84.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1000279-69-5 | 储存条件 |
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| 分子式 | C20H19ClN2O3S | 运输 | 蓝冰 | |
| 分子量 | 402.89 | 别名 |
