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CAS No.: 1235034-55-5
Synonyms: N/A
A1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 value of 70 nM in Molt-4 cell.
生物活性
靶点 | Bcl-xL EC50:70nM |
实验方案
技术信息
CAS号 | 1235034-55-5 | 储存条件 |
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分子式 | C35H32FN5O4S2 | 运输 | 蓝冰 | |||||||||||
分子量 | 669.79 | 别名 | N/A | |||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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NCI-H146 cells | - | Cytotoxicity assay | 48 hrs | Cytotoxicity against BCL-XL-dependent human NCI-H146 cells in presence of 10% human serum incubated for 48 hrs by Cell titerGlo reagent based assay, EC50=0.065 μM | 25313317 |
靶点 | Description | IC50 |
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Bcl-xL | EC50:70nM |
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