CAS No.: 103060-53-3
达托霉素 Catalog No. CSN16684
Synonyms: LY146032;Cidecin;Cubicin
Daptomycin is a lipopeptide antimicrobial agent with activity against Gram-positive organisms, including multi-resistant strains.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01551719 Infection of Skin and/or Subcu... more >>taneous Tissue Collapse << Not Applicable Withdrawn March 2013 Italy ... more >> University of Naples Federico II Naples, Italy, I-80131 Collapse << NCT03245879 Inappropriate Prescribing ... more >> Antibiotic Stewardship Anti-Bacterial Agents Collapse << Not Applicable Completed - - NCT03466502 Clostridium Difficile Infectio... more >>n Collapse << Phase 4 Enrolling by invitation March 2019 United States, Nevada ... more >> Renown Regional Medical Center Reno, Nevada, United States, 89502 Collapse << - 更多
- 参考文献
- [1] Silverman JA, Perlmutter NG, Shapiro HM. Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureus. Antimicrob Agents Chemother. 2003 Aug;47(8):2538-44.
- [2] Rybak MJ, Hershberger E, et al. In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against Staphylococci and Enterococci, including vancomycin- intermediate and -resistant strains. Antimicrob Agents Chemother. 2000 Apr;44(4):1062-6.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 103060-53-3 | 储存条件 |
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| 分子式 | C72H101N17O26 | 运输 | 蓝冰 | |||||||
| 分子量 | 1620.67 | 别名 | LY146032;Cidecin;Cubicin;达托霉素 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT01551719 | Infection of Skin and/or Subcu... more >>taneous Tissue Collapse << | Not Applicable | Withdrawn | March 2013 | Italy ... more >> University of Naples Federico II Naples, Italy, I-80131 Collapse << |
| NCT03245879 | Inappropriate Prescribing ... more >> Antibiotic Stewardship Anti-Bacterial Agents Collapse << | Not Applicable | Completed | - | - |
| NCT03466502 | Clostridium Difficile Infectio... more >>n Collapse << | Phase 4 | Enrolling by invitation | March 2019 | United States, Nevada ... more >> Renown Regional Medical Center Reno, Nevada, United States, 89502 Collapse << |
| NCT03335592 | - | - | Completed | - | France ... more >> Centre de Référence des Infections Ostéo-Articulaires complexes (CRIOAc Lyon) Lyon, France, 69004 Collapse << |
| NCT01191840 | Bacteremia | Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama, Birmingham Birmingham, Alabama, United States, 35294 United States, California David Geffen School of Medicine UCLA Los Angeles, California, United States, 90095 United States, Colorado University of Colorado Denver, Colorado, United States, 80204 United States, Massachusetts University of Mass Worcester, Massachusetts, United States, 01752 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 William Beaumont Hospital Royal Oak, Michigan, United States, 48073 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 United States, New York Albert Einstein College of Medicine Bronx, New York, United States, 10467 United States, North Carolina Carolina Medical Center Charlotte, North Carolina, United States, 28207 Duke University Medical Center Durham, North Carolina, United States, 27705 Brody School of Medicine at ECU Greenville, North Carolina, United States, 27834 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 Greenville Hospital System Greenville, South Carolina, United States, 29605 United States, Texas UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Spain Fundacio Clinic Privada per a la Recera Barcelona, Spain, 08036 Collapse << |
| NCT02539407 | - | - | Recruiting | December 2023 | France ... more >> Hospital Necker - Enfants Malades (Public Hospitals of Paris) Recruiting Paris, France, 75015 Contact: Oualha Mehdi, MD,PhD +33171196082 Collapse << |
| NCT03481569 | Infection | Phase 1 | Recruiting | October 2020 | France ... more >> CHU of Poitiers Recruiting Poitiers, France, 86000 Contact: Nadia IMZI Principal Investigator: Claire DAHYOT-FIZELIER, MD Collapse << |
| NCT01201031 | - | - | Completed | - | Taiwan ... more >> Taipei Medical University-WanFang Hospital Taipei, Taiwan Collapse << |
| NCT01359358 | - | - | Unknown | - | Brazil ... more >> Instituto de Física de Sao Carlos - Universidade de Sao Paulo Active, not recruiting Sao Carlos, Sao Paulo, Brazil, 13560-590 Collapse << |
| NCT02168816 | Osteomyelitis | Phase 2 | Terminated(The study was stopp... more >>ed for feasibility (i.e., low recruitment)) Collapse << | - | United States, Illinois ... more >> Loyola University Medical Center Maywood, Illinois, United States, 60153 Collapse << |
| NCT03081273 | - | - | Completed | - | France ... more >> Centre de reference des infections ostéo-articulaires- Hôpital de la Croix Rousse Lyon, France, 69004 Collapse << |
| NCT02168816 | - | - | Terminated(The study was stopp... more >>ed for feasibility (i.e., low recruitment)) Collapse << | - | - |
| NCT01792804 | Staphylococcus Aureus Infectio... more >>n Collapse << | Phase 3 | Recruiting | October 2019 | - |
| NCT02365493 | Methicillin-Resistant Staphylo... more >>coccus Aureus Collapse << | Phase 3 | Active, not recruiting | October 24, 2018 | Australia, New South Wales ... more >> Blacktown Hospital Blacktown, New South Wales, Australia, 2148 Royal Prince Alfred Hospital Camperdown, New South Wales, Australia, 2050 Concord Repatriation General Hospital Concord, New South Wales, Australia, 2139 St Vincent's Hospital Darlinghurst, New South Wales, Australia, 2010 Nepean Hospital Kingswood, New South Wales, Australia, 2747 Liverpool Hospital Liverpool, New South Wales, Australia, 2170 John Hunter Hospital New Lambton Heights, New South Wales, Australia, 2305 Westmead Hospital Westmead, New South Wales, Australia, 2145 Wollongong Hospital Wollongong, New South Wales, Australia, 2500 Australia, Northern Territory Royal Darwin Hospital Darwin, Northern Territory, Australia, 0820 Australia, Queensland Cairns Hospital Cairns, Queensland, Australia, 4870 Royal Brisbane and Women's Hospital Herston, Queensland, Australia, 4029 Princess Alexandra Hospital Woolloongabba, Queensland, Australia, 4102 Australia, South Australia Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Flinder's Medical Centre Bedford Park, South Australia, Australia, 5042 The Queen Elizabeth Hospital Woodville South, South Australia, Australia, 5011 Australia, Victoria Monash Medical Centre Clayton Campus Clayton, Victoria, Australia, 3168 Dandenong Hospital Dandenong, Victoria, Australia, 3175 Western Health - Footscray Footscray, Victoria, Australia, 3011 Austin Hospital Heidelberg, Victoria, Australia, 3084 Western Health - Sunshine Hospital Sunshine, Victoria, Australia, 3021 Western Health - Williamstown Hospital Williamstown, Victoria, Australia, 3016 Australia, Western Australia Fiona Stanley Hospital Murdoch, Western Australia, Australia, 6150 Royal Perth Hospital Perth, Western Australia, Australia, 6000 Israel Rambam Health Corporation Haifa, Israel Beilinson Hospital Petah Tikva, Israel New Zealand Middlemore Hospital Otahuhu, Auckland, New Zealand, 1640 Singapore Tan Tock Seng Hospital Novena, Tan Tock Seng, Singapore, 308433 National University Hospital Kent Ridge, Singapore, 119074 Singapore General Hospital Outram Park, Singapore, 168753 Collapse << |
| NCT01734694 | Health Care Associated Pneumon... more >>ia Osteomyelitis/Septic Arthritis Endocarditis Bacteremia Acute Bacterial Skin and Skin Structure Infections Collapse << | Phase 4 | Terminated(Independent biostat... more >>istician recommended early termination of the trial due to low probability of success.) Collapse << | - | United States, Michigan ... more >> Henry Ford Hospital Detroit, Michigan, United States, 48208 Collapse << |
| NCT01191840 | - | - | Completed | - | - |
| NCT01301638 | - | - | Unknown | - | Taiwan ... more >> Far Eastern Memorial Hospital Not yet recruiting Taipei, Taiwan, 220 Contact: Men_Shan Hsu, Medicine degree 886-2-7728-1849 Collapse << |
| NCT00451373 | Acute Renal Failure ... more >> Sepsis Postoperative Collapse << | Not Applicable | Unknown | December 2012 | Taiwan ... more >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Contact: Wen-Jo Ko, MD, PhD +886-2-23562082 kdw@ntumc.org Sub-Investigator: Wen-Jo Ko, MD, PhD Sub-Investigator: Vin-Cent Wu, MD Collapse << |
| NCT02208063 | Bacteremia | Phase 3 | Terminated(Halted due to lack ... more >>of statistical power. No safety concerns identified. Enrolled subjects were allowed to complete scheduled study activities.) Collapse << | - | United States, Ohio ... more >> Remington-Davis Clinical Research Columbus, Ohio, United States, 43215 Collapse << |
| NCT03426761 | Bone Infection ... more >> Osteomyelitis Septic Arthritis Joint Infection Prosthetic Joint Infection Collapse << | Phase 4 | Recruiting | January 2021 | United States, Virginia ... more >> Infectious Diseases Physicians, Inc. Recruiting Annandale, Virginia, United States, 22003 Contact: Donald Poretz, MD 703-560-4821 donald2750@aol.com Contact: David Wheeler, MD 703-560-4821 dwheel423@verizon.net Principal Investigator: Donald Poretz, MD Sub-Investigator: David Wheeler, MD Collapse << |
| NCT01612052 | MRSA - Methicillin Resistant S... more >>taphylococcus Aureus Infection Collapse << | Phase 4 | Unknown | October 2013 | United States, West Virginia ... more >> Vascular Center of Excellence Recruiting Charleston, West Virginia, United States, 25304 Contact: Patrick Stone, M.D. 304-388-8250 ext 9901 Sub-Investigator: Steven Hass, M.D. Sub-Investigator: Albier Mousa, M.D. Sub-Investigator: Ali F AbuRhama, M.D. Collapse << |
| NCT01211470 | Acute Bacterial Skin and Skin-... more >>structure Infection(ABSSSI) Due to Staphylococcus Aureus (MSSA) (Susceptible or Methicillin Resistant) Collapse << | Phase 2 | Completed | - | Canada, Ontario ... more >> Hamilton, Ontario, Canada, L8N 4A6 Canada, Quebec Chicoutimi, Quebec, Canada, G7H 5H6 Greenfield Park, Quebec, Canada, J4V 2H1 Sherbrooke, Quebec, Canada, J1H 5N4 Trois-Rivieres, Quebec, Canada, G8Z 3R9 Canada Quebec, Canada, G1V 4X7 Russian Federation 11 Sites Multiple, Russian Federation Ukraine 5 Sites Multiple, Ukraine Collapse << |
| NCT01701219 | Staphylococcus Aureus Bacterem... more >>ia Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia Collapse << | Phase 4 | Completed | - | - |
| NCT00770341 | Staphylococcal Infection | Phase 3 | Completed | - | - |
| NCT01212601 | - | - | Completed | - | China, Beijing ... more >> Research Site Beijing, Beijing, China China, Fujian Research Site Fuzhou, Fujian, China Research Site Xiamen, Fujian, China Research Site Zhangzhou, Fujian, China China, Guangdong Research Site Guangzhou, Guangdong, China China, Hebei Research Site Xingtai, Hebei, China China, Heilongjiang Research Site Haerbing, Heilongjiang, China China, Henan Research Site Zhenzhou, Henan, China China, Hubei Research Site Wuhan, Hubei, China China, Jiangsu Research Site Changzhou, Jiangsu, China Research Site Nanjing, Jiangsu, China Research Site Nantong, Jiangsu, China Research Site Suzhou, Jiangsu, China China, Liaoning Research Site Dalian, Liaoning, China China, Shanghai Research Site Shanghai, Shanghai, China China, Sichuan Research Site Chengdu, Sichuan, China China, Tianjin Research Site Tianjin, Tianjin, China China, Yunnan Research Site Kunming, Yunnan, China Collapse << |
| NCT00770341 | - | - | Completed | - | - |
| NCT00540072 | Pneumonia, Bacterial | Phase 3 | Completed | - | - |
| NCT03138733 | Staphylococcus Aureus Bacterem... more >>ia Collapse << | Phase 3 | Recruiting | August 2021 | United States, Alabama ... more >> 6701 Airport Boulevard Recruiting Mobile, Alabama, United States, 36608 Contact: Nolan, PI United States, California eStudy Site - Chula Vista - PPDS Recruiting Chula Vista, California, United States, 91911 Contact: Waters, PI eStudy Site - La Mesa - PPDS Recruiting La Mesa, California, United States, 91942 Contact: Overcash, PI United States, Florida Yaneicy Recruiting Coral Gables, Florida, United States, 33134 Contact: Gonzales-Rojas, PI Triple O Medical Services Inc Recruiting West Palm Beach, Florida, United States, 33407 Contact: Osijemi, PI United States, Montana Mercury Street Medical Group Recruiting Butte, Montana, United States, 59701 Contact: Pullman, PI United States, Nevada eStudy Site - Las Vegas - PPDS Recruiting Las Vegas, Nevada, United States, 89109 Contact: Shockley, PI United States, Ohio 3820 Olentangy River Road Recruiting Columbus, Ohio, United States, 43214 Contact: Baird, PI Collapse << |
| NCT01287832 | Bacteremia | Phase 4 | Terminated(Low patient enrollm... more >>ent) Collapse << | - | - |
| NCT02660346 | Bacteremia | Phase 4 | Completed | - | United States, California ... more >> Sharp Grossmont Hospital La Mesa, California, United States, 91942 Sharp Memorial Hospital San Diego, California, United States, 92123 Collapse << |
| NCT01287832 | - | - | Terminated(Low patient enrollm... more >>ent) Collapse << | - | - |
| NCT00426933 | Soft Tissue Infections | Phase 2 | Completed | - | United States, Idaho ... more >> Idaho Falls Infectious Diseases, PLLC Idaho Falls, Idaho, United States, 83404 Collapse << |
| NCT00772447 | Skin Diseases ... more >> Infectious Collapse << | Phase 3 | Completed | - | China, Beijing ... more >> Research Site Beijing, Beijing, China China, Guangdong Research Site Guangzhou, Guangdong, China China, Hubei Research Site Wuhan, Hubei, China China, Hunan Research Site Changsha, Hunan, China China, Jiangsu Research Site Nanjing, Jiangsu, China Research Site Suzhou, Jiangsu, China China, Liaoning Research Site Shenyang, Liaoning, China China, Shanghai Research Site Shanghai, Shanghai, China China, Sichuan Research Site Chengdu, Sichuan, China China Research Site Chongqing, China Research Site Dalian, China Research Site Hangzhou, China Research Site Qingdao, China Collapse << |
| NCT01314053 | - | - | Unknown | April 2011 | Taiwan ... more >> Taipei Medical University - WanFang Hospital Taipei, Taiwan Collapse << |
| NCT01219114 | - | - | Withdrawn(Inability to recruit... more >> patients within the specified time period. No patients have been enrolled in the study.) Collapse << | November 2013 | Philippines ... more >> Research Site Lipa City, Batangas, Philippines Research Site Davao City, Davao, Philippines Research Site Iloilo City, Iloilo, Philippines Research Site Pasig City, Metro Manila, Philippines Research Site Quezon City, Metro Manila, Philippines Collapse << |
| NCT00428844 | Osteomyelitis | Phase 2 | Completed | - | - |
| NCT03134521 | - | - | Active, not recruiting | June 30, 2017 | - |
| NCT00428844 | - | - | Completed | - | - |
| NCT00055198 | Gram-Positive Bacterial Infect... more >>ions Collapse << | Phase 3 | Terminated(Study terminated du... more >>e to low enrollment) Collapse << | - | - |
| NCT01306825 | - | - | Unknown | November 2015 | France ... more >> Service d'Orthopédie - Hôpital Centre de Chirurgie Orthopédie et de la Main (CCOM) - Hôpitaux Universitaires de Strasbourg - 10 av Achille Baumann - Recruiting Illkirch-Graffenstaden, France, 67400 Contact: Jeannot GAUDIAS, MD 33 3 88 55 23 45 jeannot.gaudias@chru-strasbourg.fr Principal Investigator: Jeannot GAUDIAS, MD Sub-Investigator: Cyril BOERI, MD Plateau Technique de Microbiologie - Hôpitaux Universitaires de Strasbourg - 1, rue Koeberlé Recruiting Strasbourg, France, 67000 Contact: JEHL François, PHARM D 33 3 68 85 37 81 francois.jehl@chru-strasbourg.fr Sub-Investigator: François JEHL, PARM D Service des maladies infectieuses et tropicales - Nouvel Hôpital Civil - Hôpitaux Universitaires de Strasbourg Recruiting Strasbourg, France, 67091 Contact: Nicolas Lefebvre, MD 33 3 69 55 05 45 nicolas.lefebvre@chru-strasbourg.fr Principal Investigator: Nicolas Lefebvre, MD Sub-Investigator: Daniel CHRISTMANN Daniel, MD, PhD Sub-Investigator: Yves HANSMANN, MD, PhD Collapse << |
| NCT00136292 | Gram-positive Bacterial Infect... more >>ions Collapse << | Phase 1 | Completed | - | United States, Arkansas ... more >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72202 United States, Missouri Children's Mercy Hospitals and Clinics Kansas City, Missouri, United States, 64108 United States, Texas University of Texas Southwestern Dallas, Texas, United States, 75390 Collapse << |
| NCT01212432 | Gram-Positive Bacterial Infect... more >>ions Collapse << | Phase 2 | Unknown | March 2010 | Switzerland ... more >> Recruiting Zurich, Switzerland Collapse << |
| NCT02052388 | Skin Infection ... more >> Bacterial Infection Collapse << | Phase 2 | Completed | - | United States, California ... more >> eStudy Site Chula Vista, California, United States, 91911 eStudy Site La Mesa, California, United States, 91942 eStudy Site Oceanside, California, United States, 92056 United States, Nevada eStudy Site Las Vegas, Nevada, United States, 89109 Collapse << |
| NCT01133600 | Diabetic Foot | Phase 4 | Terminated(Lack of patient enr... more >>ollment) Collapse << | - | United States, Virginia ... more >> Clinical Alliance for Research & Education, Infectious Diseases, LlC Annandale, Virginia, United States, 22003 Infuscience Annandale, Virginia, United States, 22003 Collapse << |
| NCT01592032 | Catheter-Related Infections ... more >> Bacteremia. Collapse << | Phase 4 | Unknown | December 2015 | Spain ... more >> Clinica Universidad de Navarra Pamplona, Navarra, Spain, 31008 Collapse << |
| NCT00967941 | MRSA Infections | Phase 4 | Completed | - | United States, West Virginia ... more >> Vascular Center of Excellence Charleston, West Virginia, United States, 25304 Collapse << |
| NCT00538694 | Pneumonia, Bacterial | Phase 3 | Completed | - | - |
| NCT01626560 | Cellulitis | Phase 4 | Completed | - | Brazil ... more >> Hospital Universitário Evangelico de Curitiba Curitiba, Parana, Brazil, 80730150 Collapse << |
| NCT01104662 | Complicated Skin and Skin Stru... more >>cture Infections S. Aureus Bacteremia Renal Impairment Collapse << | Phase 4 | Terminated(Cubist has reached ... more >>an agreement with the FDA that enrollment in the DAP-RENSE-08-05 study can stop.) Collapse << | - | United States, California ... more >> Azusa, California, United States Los Angeles, California, United States Torrance, California, United States United States, District of Columbia Washington, District of Columbia, United States United States, Georgia Decatur, Georgia, United States United States, New Jersey Somers Point, New Jersey, United States United States, North Carolina Winston-Salem, North Carolina, United States United States, Ohio Columbus, Ohio, United States United States, Pennsylvania West Reading, Pennsylvania, United States United States, Texas Mission, Texas, United States Collapse << |
| NCT00093067 | Bacterial Endocarditis ... more >> Bacteremia Collapse << | Phase 3 | Completed | - | - |
| NCT01104662 | - | - | Terminated(Cubist has reached ... more >>an agreement with the FDA that enrollment in the DAP-RENSE-08-05 study can stop.) Collapse << | - | - |
| NCT00295178 | Cellulitis | Phase 4 | Completed | - | United States, Georgia ... more >> Joseph Still Research Foundation Augusta, Georgia, United States, 30909 Collapse << |
| NCT00430937 | - | - | Terminated | - | - |
| NCT00651131 | Wound Infections | Phase 4 | Terminated(terminated due to s... more >>low enrollment) Collapse << | - | - |
| NCT00573898 | - | - | Completed | - | United States, Pennsylvania ... more >> UPMC PIttsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00772447 | - | - | Completed | - | - |
| NCT00572260 | Antimicrobial Prophylaxis | Phase 4 | Terminated(Study closed. PI le... more >>ft the institution.) Collapse << | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00572260 | - | - | Terminated(Study closed. PI le... more >>ft the institution.) Collapse << | - | - |
| NCT00430937 | Skin Diseases, Infectious ... more >> Soft Tissue Infections Collapse << | Phase 3 | Terminated | - | - |
| NCT01175707 | Complicated Skin or Skin Struc... more >>ture Infection Collapse << | Phase 4 | Terminated(Business decision) | - | United States, Michigan ... more >> Heartland I.V. Care Livonia, Michigan, United States, 48150 United States, Minnesota Heartland I.V. Care Roseville, Minnesota, United States, 55113 United States, Pennsylvania Heartland I.V. Care Pittsburgh, Pennsylvania, United States, 15220 United States, Texas NationsMed Clinical Research, Inc. Stafford, Texas, United States, 77477 Collapse << |
| NCT01455246 | Cirrhosis Asc... more >>ites Nosocomial Spontaneous Bacterial Peritonitis Collapse << | Phase 2 Phase 3 | Terminated(Decision of indepen... more >>dent monitoring committee after interim analysis Risk of failure significantly higher in ceftazidime group.) Collapse << | - | Italy ... more >> Dept. of Clinical and Experimental Medicine, University of Padova Padova, PD, Italy, 35128 Collapse << |
| NCT01175707 | - | - | Terminated(Business decision) | - | - |
| NCT01922011 | Acute Hematogenous Osteomyelit... more >>is Collapse << | Phase 3 | Completed | - | - |
| NCT00296049 | Infection Neu... more >>tropenia Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific Collapse << | Not Applicable | Withdrawn | - | United States, North Carolina ... more >> Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 Collapse << |
| NCT01898338 | Staph Aureus Methicillin Resis... more >>tant Bacteremia Collapse << | Phase 3 | Completed | - | Spain ... more >> Hospital Universitari de Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Hospital Parc Taulí Sabadell, Barcelona, Spain, 08208 Hospital Universitari Mútua de Terrassa Terrassa, Barcelona, Spain, 08221 Hospital de Terrassa Terrassa, Barcelona, Spain, 08227 Hospital Universitario de Cruces Barakaldo, Spain, 48903 Hospital del Mar- Parc de Salut Mar Barcelona, Spain, 08003 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Hospital Vall d'Hebron Barcelona, Spain, 08035 Hospital Clinic Barcelona, Spain, 08036 Hospital Universitario Virgen de las Nieves Granada, Spain, 18014 Hospital Universitari Arnau de Vilanova Lleida, Spain, 25198 Hospital Universitario Lucus Augusti Lugo, Spain, 27004 Hospital General Gregorio Marañon Madrid, Spain, 28007 Hospital Ramon y Cajal Madrid, Spain, 28034 Hospital Universitario 12 de Octubre Madrid, Spain, 28041 Complejo Asistencial Son Espases Palma de Mallorca, Spain, 07120 Hospital Virgen Macarena Sevilla, Spain, 41071 Hospital Universitari Joan XXIII Tarragona, Spain, 43007 Collapse << |
| NCT01922011 | - | - | Completed | - | - |
| NCT00490737 | End-Stage Renal Disease | Phase 1 | Completed | - | - |
| NCT00102947 | Soft Tissue Infections | Phase 4 | Terminated | - | United States, California ... more >> Harbor UCLA Medical Center Torrance, California, United States, 90509 United States, Florida Tampa General Hospital Tampa, Florida, United States, 33606 United States, Georgia Joseph M. Still Research Institute Augusta, Georgia, United States United States, Minnesota Infectious Diseases Minneapolis-LTD Minneapolis, Minnesota, United States, 55422 United States, New York Upstate Clinical Research Associates Buffalo, New York, United States, 14203 University of Rochester Medical Center Rochester, New York, United States, 14642 United States, North Carolina AllTrials Clinical Research Winston-Salem, North Carolina, United States, 27103 United States, Ohio Riverside Methodist Hospital Columbus, Ohio, United States, 43215 Wright State University/Veterans Affairs Medical Center Dayton, Ohio, United States, 45428 ID Clinical Research Toledo, Ohio, United States, 43608 United States, Pennsylvania St. Luke's Hospital Bethlehem, Pennsylvania, United States, 19015 The Reading Hospital and Medical Center West Reading, Pennsylvania, United States, 19610 Collapse << |
| NCT01184872 | - | - | Completed | - | - |
| NCT01184872 | Infections | Phase 3 | Completed | - | Austria ... more >> Novartis Investigative Site Graz, Austria Novartis Investigative Site Vienna, Austria Germany Novartis Investigative Site Bochum, Germany Novartis Investigative Site Essen, Germany Novartis Investigative Site Homburg, Germany Novartis Investigative Site Magdeburg, Germany Novartis Investigative Site Mannheim, Germany Novartis Investigative Site Muenster, Germany Novartis Investigative Site Tuebingen, Germany Italy Novartis Investigative Site Pisa, Italy Russian Federation Novartis Investigative Site (1) Moscow, Russian Federation Novartis Investigative Site Novosibirsk, Russian Federation Novartis Investigative Site (2) Saint Petersburg, Russian Federation Novartis Investigative Site Yaroslavi, Russian Federation Spain Novartis Investigative Site (1) Madrid, Spain Novartis Investigative Site Santander, Spain Novartis Investigative Site Seville, Spain Collapse << |
| NCT01549613 | - | - | Completed | - | - |
| NCT01549613 | Cellulitis Sk... more >>in Infections Collapse << | Phase 4 | Completed | - | United States, Ohio ... more >> University of Cincinnati, Dept. of Emergency Medicine Cincinnati, Ohio, United States, 45267 Collapse << |
| NCT03588637 | - | - | Recruiting | December 30, 2021 | China, Sichuan ... more >> West China Hospital Recruiting Chengdu, Sichuan, China, 610041 Contact: Xuelian Liao, MD Collapse << |
| NCT00858325 | Healthy | Phase 1 | Completed | - | China ... more >> Research Site Beijing, China Collapse << |
| NCT01171547 | Bacteremia | Phase 2 | Unknown | - | Switzerland ... more >> Medical Intensive Care Unit, University Hospital Zurich Recruiting Zurich, Switzerland, 8091 Contact: Maggiorini, Prof marco.maggiorini@usz.ch Collapse << |
| NCT00695903 | - | - | Terminated(terminated due to l... more >>ack of enrollment) Collapse << | - | - |
| NCT00261807 | Fasciitis, Necrotizing ... more >> Severe Necrotizing Skin and Soft Tissue Infections Fournier's Gangrene Collapse << | Not Applicable | Completed | - | United States, Maryland ... more >> R Adams Cowley Shock Trauma Center, U. of Maryland Medical Center Baltimore, Maryland, United States, 21201 Collapse << |
| NCT00711802 | Skin Diseases, Infectious | Phase 4 | Completed | - | - |
| NCT00695903 | Endocarditis, Bacterial ... more >> Infective Endocarditis Collapse << | Phase 2 | Terminated(terminated due to l... more >>ack of enrollment) Collapse << | - | United States, North Carolina ... more >> East Carolina University Greenville, North Carolina, United States United States, Ohio Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Collapse << |
| NCT01216241 | - | - | Terminated(The study has shown... more >> futility and the objectives could not be reached without enrolling a very large number of subjects.) Collapse << | - | - |
| NCT01080963 | Wound Infection | Phase 4 | Completed | - | Germany ... more >> Hannover Medical School, Department of Cardiothoracic, Transplant and Vascular surgery Hannover, Germany Collapse << |
| NCT00711802 | - | - | Completed | - | - |
| NCT00467272 | Bloodstream Infection | Phase 2 | Completed | - | United States, Texas ... more >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT02142075 | Renal Failure ... more >> Critical Care Gram Positive Bacteria Collapse << | Phase 3 | Completed | - | France ... more >> Lasocki S, University Hospital of Angers Angers, France, 49933 Asehnoune K, University Hospital of Nantes Nantes, France, 44093 Seguin P, University Hospital of Rennes Rennes, France, 35033 Ferrandiere M, University Hospital of Tours Tours, France, 37170 Collapse << |
| NCT01216241 | Febrile Neutropenia | Phase 3 | Terminated(The study has shown... more >> futility and the objectives could not be reached without enrolling a very large number of subjects.) Collapse << | - | United States, New York ... more >> University of Rochester Medical Center Rochester, New York, United States, 14642 Collapse << |
| NCT03480191 | Pneumococcal Meningitis | Phase 2 | Recruiting | September 2021 | France ... more >> CHU Dijon Bourgogne Recruiting Dijon, France, 21000 Contact: Pascal CHAVANET, MD 03 80 29 33 05 pascal.chavanet@chu-dijon.fr Collapse << |
| NCT00882557 | - | - | Completed | - | - |
| NCT00882557 | End-stage Renal Disease ... more >> Renal Failure Chronic Requiring Hemodialysis Collapse << | Phase 1 | Completed | - | United States, California ... more >> West Coast Clinical Trials Cypress, California, United States, 90630 United States, Minnesota DaVita Clinical Research Minneapolis, Minnesota, United States, 55404 Collapse << |
| NCT01419184 | - | - | Completed | - | - |
| NCT01019395 | Gram Positive Bacterial Infect... more >>ion Collapse << | Phase 1 | Completed | - | United States, Arkansas ... more >> Arkansas Children's Hospital Little Rock, Arkansas, United States, 72202 United States, California Children's Hospital of Orange County Orange, California, United States, 92868 Rady Children's Hospital-San Diego San Diego, California, United States, 92123 United States, Louisiana University of Louisiana at Monroe Shreveport, Louisiana, United States, 71103 United States, Missouri Children's Mercy Hospital and Clinics Kansas City, Missouri, United States, 64108 United States, Ohio University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 Toledo Children's Hospital Toledo, Ohio, United States, 43606 United States, Texas Cook Children's Medical Center Fort Worth, Texas, United States, 76104 Collapse << |
| NCT01199783 | Diabetic Foot | Phase 3 | Terminated(Patient number to b... more >>e enrolled not reachable in prospected time frame, decision to stop the study prematurely was made.) Collapse << | - | Germany ... more >> Herz- und Diabeteszentrum Bad Oeynhausen, Germany, 32545 Collapse << |
| NCT00507247 | Staphylococcus Aureus | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01419184 | Staphylococcal Skin Infections | Phase 4 | Completed | - | - |
| NCT01728376 | Bacteremia | Phase 4 | Completed | - | - |
| NCT01728376 | - | - | Completed | - | - |
| NCT00463801 | Staphylococcal Skin Infections | Phase 4 | Terminated(Because of inadequa... more >>te accrual.) Collapse << | - | Italy ... more >> Novartis Italy Novartis Italy, Italy Novartis Italy Saronno, Italy Collapse << |
| NCT00401960 | Endocarditis, Bacterial | Phase 4 | Terminated(inadequate enrollme... more >>nt) Collapse << | - | United States, New York ... more >> NewYork-Presbyterian Hospital, Weill Cornell Campus New York, New York, United States, 10021 Collapse << |
| NCT00463801 | - | - | Terminated(Because of inadequa... more >>te accrual.) Collapse << | - | - |
| NCT01515020 | Nosocomial Infection ... more >> Healthcare-associated Infection Collapse << | Phase 3 | Terminated(lack of inclusion) | - | France ... more >> Hopital Beaujon Clichy cedex, France, 92118 Collapse << |
| NCT00401960 | - | - | Terminated(inadequate enrollme... more >>nt) Collapse << | - | - |
| NCT00663403 | - | - | Completed | - | - |
| NCT02000414 | Peritoneal Infection | Not Applicable | Completed | - | France ... more >> Néphrologie CHU de Caen Caen, France, 14000 Collapse << |
| NCT00638157 | Infective Endocarditis | Phase 4 | Terminated(commitment complete... more >>d) Collapse << | - | United States, Colorado ... more >> Denver Health Medical Center Denver, Colorado, United States, 80204 United States, Michigan Wayne State University Detroit, Michigan, United States, 48201 Henry Ford Health System Detroit, Michigan, United States, 48202 United States, Pennsylvania Temple University School of Medicine Philadelphia, Pennsylvania, United States, 19140 Collapse << |
| NCT00638157 | - | - | Terminated(commitment complete... more >>d) Collapse << | - | - |
| NCT00335478 | Fever Sweatin... more >>g Hot Flashes Infection Neutropenia Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Completed | - | United States, Oregon ... more >> OHSU Knight Cancer Institute Portland, Oregon, United States, 97239 Collapse << |
| NCT01025271 | Meningitis | Not Applicable | Terminated(unable to enroll su... more >>bjects study stopped due to lack of enrollment) Collapse << | - | United States, Pennsylvania ... more >> UPMC PIttsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00335478 | - | - | Completed | - | - |
| NCT00663403 | Critically Ill ... more >> Hemodialysis Collapse << | Phase 4 | Completed | - | United States, Michigan ... more >> University of Michigan University Hospital Ann Arbor, Michigan, United States, 48109 Collapse << |
| NCT03209934 | - | - | Completed | - | - |
| NCT01025271 | - | - | Terminated(unable to enroll su... more >>bjects study stopped due to lack of enrollment) Collapse << | - | - |
| NCT00942149 | - | - | Completed | - | - |
| NCT00701636 | Late Effects of Surgery ... more >> Staphylococcus Aureus Surgical Site Infection Collapse << | Phase 3 | Completed | - | United States, California ... more >> Harbor-UCLA Medical Center Torrance, California, United States, 90509 Collapse << |
| NCT00679835 | Gram Positive Infection ... more >> Concurrent Antibiotic Treatment Collapse << | Phase 1 | Completed | - | United States, Missouri ... more >> Children's Mercy Hospital Kansas City, Missouri, United States, 64108 Collapse << |
| NCT01012089 | Chronic Kidney Disease ... more >> Bacterial Infection Collapse << | Not Applicable | Completed | - | United States, Oklahoma ... more >> The Children's Hospital at the University of Oklahoma Medical Center Oklahoma City, Oklahoma, United States, 73013 Collapse << |
| NCT01012089 | - | - | Completed | - | - |
| NCT00701636 | - | - | Completed | - | - |
| NCT01522105 | Meningitis | Phase 1 | Terminated(Insufficient patien... more >>t recruitment) Collapse << | - | Switzerland ... more >> Dep. of Pediatrics, University Hospital Bern Bern, Switzerland, 3010 Collapse << |
| NCT00942149 | Sepsis | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT03004066 | - | - | Recruiting | April 2019 | Germany ... more >> University Hospital Tuebingen Recruiting Tuebingen, Germany, 72076 Contact: Stefanie Prohaska, MD +497071 29 ext 86724 stefanie.prohaska@med.uni-tuebingen.de Principal Investigator: Helene A Haeberle, MD Collapse << |
| NCT03209921 | - | - | Completed | - | - |
| NCT01144000 | Staphylococcal Infections | Phase 2 | Unknown | June 2016 | Switzerland ... more >> Centre hospitaliere universitaire vaudois (CHUV) Not yet recruiting Lausanne, Vaud, Switzerland, 1011 Contact: Andrej Trampuz +41 (0)21 314 39 92 andrej.trampuz@chuv.ch Principal Investigator: Olivier Borens Kantonsspital Not yet recruiting Liestal, Switzerland, 4410 Contact: Werner Zimmerli, MD +41 61 925 1111 werner.zimmerli@ksli.ch Contact: Martin Clauss, MD martin.clauss@ksli.ch Principal Investigator: Werner Zimmerli, MD Sub-Investigator: Martin Clauss, MD Schulhess Clinic Not yet recruiting Zurich, Switzerland, 8008 Contact: Markus Vogt, MD markus.vogt@zgks.ch Principal Investigator: Markus Vogt, MD Collapse << |
| NCT01975662 | Bacteremia Due to Staphylococc... more >>us Aureus Collapse << | Phase 2 | Terminated(slow accrual of par... more >>ticipants) Collapse << | - | Singapore ... more >> Singapore General Hospital Singapore, Singapore, 169608 Collapse << |
| NCT02241941 | Burn Injury | Phase 4 | Withdrawn(Assessment of daptom... more >>ycin concentrations with microdialysis technically not feasible) Collapse << | - | Switzerland ... more >> University Hospital Zurich Zurich, Switzerland, 8091 Collapse << |
| NCT02508350 | Septic Shock | Not Applicable | Unknown | June 2016 | China, Jiangsu ... more >> Zhongda hospital, Southeast University Recruiting Nanjing, Jiangsu, China, 210009 Contact: Nan Guo 15850681416 guonan8910@163.com Collapse << |
| NCT02097953 | Drug Interactions ... more >> Pharmacokinetics Collapse << | Early Phase 1 | Completed | - | United States, Utah ... more >> University of Utah Salt Lake City, Utah, United States, 84132 Collapse << |
| NCT01196169 | Staphylococcal Infections ... more >> Methicillin-resistant Staphylococcus Aureus Collapse << | Phase 4 | Terminated(The study is closed... more >> to accrual. Enrollment of new patients stopped at the request of CUBIST Pharmaceuticals due to slow rate of enrollment.) Collapse << | March 2014 | United States, Tennessee ... more >> Johnson City Medical Center Johnson City, Tennessee, United States, 37604 James H Quillen VA Medical Center Mountain Home, Tennessee, United States, 37684 Collapse << |
| NCT03643952 | Bacteremia So... more >>ft Tissue Infections Skin Diseases, Infectious Collapse << | Phase 2 | Recruiting | May 14, 2021 | Japan ... more >> Japan Community Health Care Organization Chukyo Hospital ( Site 0030) Recruiting Nagoya, Aichi, Japan, 457-8510 Contact: Study Coordinator +81526917151 Japan Community Health care Organization Kyushu Hospital ( Site 0016) Recruiting Kitakyushu, Fukuoka, Japan, 806-8501 Contact: Study Coordinator +81936415111 Maebashi Red Cross Hospital ( Site 0012) Recruiting Maebashi, Gunma, Japan, 371-0811 Contact: Study Coordinator +81272244585 Kobe University Hospital ( Site 0015) Recruiting Kobe, Hyogo, Japan, 650-0017 Contact: Study Coordinator +81783825111 Shikoku Medical Center for Children and Adults ( Site 0027) Recruiting Zentsuji, Kagawa, Japan, 765-8507 Contact: Study Coordinator +81877621000 Showa University Fujigaoka Hospital ( Site 0023) Recruiting Yokohama, Kanagawa, Japan, 227-8501 Contact: Study Coordinator +81459711151 Kanagawa Children's Medical Center ( Site 0025) Recruiting Yokohama, Kanagawa, Japan, 232-8555 Contact: Study Coordinator +81457112351 National Hospital Organization National Mie Hospital ( Site 0002) Recruiting Tsu, Mie, Japan, 514-0125 Contact: Study Coordinator +81592322531 National Hospital Organization Beppu Medical Center ( Site 0003) Recruiting Beppu, Oita, Japan, 874-0011 Contact: Study Coordinator +81977671111 Chiba University Hospital ( Site 0005) Recruiting Chiba, Japan, 260-8677 Contact: Study Coordinator +81432227171 Chiba Children's Hospital ( Site 0024) Recruiting Chiba, Japan, 266-0007 Contact: Study Coordinator +81432922111 National Hospital Organization Kumamoto Medical Center ( Site 0018) Recruiting Kumamoto, Japan, 860-0008 Contact: Study Coordinator +81963536501 Osaka City General Hospital ( Site 0020) Recruiting Osaka, Japan, 534-0021 Contact: Study Coordinator +81669291221 Saitama City Hospital ( Site 0008) Recruiting Saitama, Japan, 336-8522 Contact: Study Coordinator +81488734111 Nihon University Itabashi Hospital ( Site 0029) Recruiting Tokyo, Japan, 173-8610 Contact: Study Coordinator +81339728111 Collapse << |
| NCT02972983 | Methicillin Susceptible Staphy... more >>lococcus Aureus Septicemia Bacteremia Collapse << | Phase 4 | Recruiting | July 2018 | Canada, Quebec ... more >> McGill University Health Centre (Royal Victoria Hospital, Montreal Neurological Hospital, and Montreal General Hospital) Recruiting Montreal, Quebec, Canada, H4A3J1 Contact: Todd C Lee, MD MPH 514-934-1934 ext 53333 todd.lee@mcgill.ca Contact: Cheng P Matthew, MD 514-934-1934 ext 53333 matthew.cheng@mail.mcgill.ca Principal Investigator: Todd C Lee, MD MPH Principal Investigator: Matthew P Cheng, MD Sub-Investigator: Alexander Lawandi, MD Sub-Investigator: Guillaume Butler-Laporte, MD Collapse << |
