CAS No.: 2752-65-0
藤黄酸 Catalog No. CSN13795
Synonyms: Gambogic acid
Gambogic acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Yi T, Yi Z, et al. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res. 2008 Mar 15;68(6):1843-50.
- [2] Zhang HZ, Kasibhatla S, et al. Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. Bioorg Med Chem. 2004 Jan 15;12(2):309-17.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2752-65-0 | 储存条件 |
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| 分子式 | C38H44O8 | 运输 | 蓝冰 | |||||||||
| 分子量 | 628.75 | 别名 | Gambogic acid | |||||||||
| 溶解度 |
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动物实验配方 |
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