|(2R,3R,4R,5R)-2-(6-氨基-9H-嘌呤-9-基)-5-(((((((2R,3S,4R,5R)-5-(3-氨基甲酰基吡啶-1(4H)-基)-3,4-二羟基四氢呋喃-2-基)甲氧基)oxidophosphoryl)氧基)oxidophosphoryl)氧基)甲基)-4-羟基四氢呋喃-3-基磷酸四钠盐|CsnPharm

CAS No.: 2646-71-1

NADPH四钠盐 Catalog No. CSN10431

Synonyms: NADPH (sodium salt);Nicotinamide adenine dinucleotide phosphate;NADPH Tetrasodium Salt

NADPH Tetrasodium salt is a ubiquitous cofactor and biological reducing agent that acts as an electron donor in many biological reactions.

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400-920-2911

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技术信息

生物活性

描述NADPH tetrasodium salt is a cofactor, used to donate electrons and hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety^[1]. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species^[2]. It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation^[3].
参考文献

[1] Sumimoto H. Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS J. 2008 Jul;275(13):3249-77
[2] Sutherland, M.W., Nelson, J., Harrison, G., et al. Effects of t-butyl hydroperoxide on NADPH, glutathione, and the respiratory burst of rat alveolar machrophages. Arch. Biochem. Biophys. 1985;243(2), 325-331.
[3] Tserng, K.Y., and Jin, S.J. NADPH-dependent reductive metabolism of cis-5 unsaturated fatty acids. A revised pathway for the β-oxidation of oleic acid. The Journal of Biological Chemisty. 1990; 266(18), 11614-11620.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.2000 mL
- 5.9999 mL
- 11.9998 mL
- 5 mM
- 0.2400 mL
- 1.2000 mL
- 2.4000 mL
- 10 mM
- 0.1200 mL
- 0.6000 mL
- 1.2000 mL

技术信息

CAS号

2646-71-1

储存条件

粉末: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H26N7Na4O17P3

运输

蓝冰

分子量

833.35

别名

NADPH (sodium salt);Nicotinamide adenine dinucleotide phosphate;NADPH Tetrasodium Salt;Dihydronicotinamide-adenine dinucleotide phosphate;tetrasodium salt;NADPH sodium salt

溶解度

DMSO	insoluble
Water	40.0 mg/mL (48.0 mM)

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