CAS No.: 7437-55-0
8-Geranyloxypsoralen/8-香叶草氧基补骨脂素 Catalog No. CSN12221
Synonyms: 8-香叶草氧基补骨脂素
8-Geranyloxypsoralen, a natural product isolated and purified from the herbs of Seseli mairei Wolff., inhibits β-secretase (BACE1) activity in non-competitive manner, with the IC(50) values < 25.0 uM. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Marumoto S, Miyazawa M. Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor. Bioorg Med Chem. 2012 Jan 15;20(2):784-8.
- [2] Row EC, Brown SA, et al. Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. Bioorg Med Chem. 2006 Jun 1;14(11):3865-71.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 7437-55-0 | 储存条件 |
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| 分子式 | C21H22O4 | 运输 | 蓝冰 | |
| 分子量 | 338.40 | 别名 | 8-香叶草氧基补骨脂素 |
