|7-羟基-6-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-2H-苯并吡喃-2-酮|CsnPharm

CAS No.: 531-75-9

秦皮甲素 Catalog No. CSN16387

Synonyms: Aesculin;Esculetin 6Dglucoside;秦皮甲素

Esculin is a glucoside isolated and purified from the peel of Aesculus hippocastanum L., possessing antiflogistic, cytostatic, and antimutagenic properties, and is used for the treatment of various peripheral vascular disorders and in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria).

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生物活性

描述Esculin is a derivative of coumarin, which is also an active ingredient of ash bark, and has antibacterial, anti-inflammatory, anti-allergy and skin protective effects ^[3]. Esculin significantly reduced the pathological symptoms of acute liver injury, as well as serum AST (Aspartate aminotransferase) and ALT (Alamine aminotransferase) levels. Furthermore, LPS/D-Gal-induced liver tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) production were attenuated by esculin^[5]. Esculin (5, 10 or 20 mg/kg ) may ameliorate cognitive impairment in experimental DN (diabetic nephropathy), and exert anti-oxidative stress and anti-inflammatory effects^[3].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.9387 mL
- 14.6937 mL
- 29.3874 mL
- 5 mM
- 0.5877 mL
- 2.9387 mL
- 5.8775 mL
- 10 mM
- 0.2939 mL
- 1.4694 mL
- 2.9387 mL

技术信息

CAS号	531-75-9	储存条件	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C15H16O9	运输	蓝冰
分子量	340.28	别名	Aesculin;Esculetin 6Dglucoside;秦皮甲素

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